Uveal Metastasis from Carcinoid Tumor

Metastatic tumors of the uvea in 38 eyes

“…Most of these malignancies are carcinomas, and the predominant primary sites of the metastatic uveal tumors are breast and lung in women, and lung and gastrointestinal tract in men. [6][7][8][9] In our series, the primary tumor type was carcinoma in all patients. As in previous studies, we found that the breast was the most common primary site, accounting for 87.5% of all uveal metastases, followed by the lung (7%).…”

“…Various series have reported an overall median survival rate of 7.4-18 months from the time of ocular diagnosis. 6,7 Patients with uveal metastasis from carcinoid tumors have been reported as having had the longest survival rate. 7 The mean time to death after ocular diagnosis was 17 months in our patients.…”

A case of presumed choroidal metastasis from carcinoid tumor treated by photodynamic therapy with verteporfin

“…Uveal metastasis is the most common intraocular malignancy and the majority originate from breast cancer in women and lung cancer in men. Uveal metastasis from carcinoid tumors constitutes only 2.2% of all uveal metastases 1–3. The survival outcome of metastatic uveal tumor is generally poor.…”

“…The mean survival is 8 months from the establishment of ocular diagnosis in cases of primary lung cancer and 18 months in cases of primary breast cancer 11. However, a relatively long survival of 34 months has been reported in cases of primary carcinoid tumor 3. Uveal carcinoid metastasis may be the initial manifestation of carcinoid tumor in some patients, or the late manifestation of advanced metastatic disease in others 5.…”

“…Uveal metastasis from carcinoid tumor constitutes a small proportion of all uveal metastases 1–3. Although photodynamic therapy (PDT) has been reported as a treatment for some cases of metastatic choroidal tumor,4 as far as we are aware, only one case report on PDT for choroidal metastasis of carcinoid tumor has been published 5.…”