UV-Induced Immune Suppression that Promotes Skin Cancer Development and Progression

Induction of Alloantigen-specific CD4+ T Regulatory Type 1 Cells by Alloantigen Immunization and Ultraviolet-B Irradiation: A Pilot Study in Murine Transplantation Models With Skin and Cardiac Allografts

“…Regulatory T cells (Tregs) are important in immunity [14][15][16][17], and alloantigenspecific immunosuppression is critical for organ transplantation [7,10,16,[18][19][20]. To date, our group has focused on applications of UV irradiation [21][22][23][24][25]. To induce alloantigen-specific Tregs, high-dose UV-B irradiation accompanied by alloantigen immunization is required [5,7,10,11,[26][27][28][29].…”