Utilizing Pharmacogenomic Data for a Safer Use of Statins among the
Emirati Population
Mais N. Alqasrawi,
Zeina N. Al-Mahayri,
Hiba Alblooshi
et al.
Abstract:Background:
Statins are the most prescribed lipid-lowering drugs worldwide. The associated
adverse events, especially muscle symptoms, have been frequently reported despite their perceived
safety. Three pharmacogenes, the solute carrier organic anion transporter family member 1B1
(SLCO1B1), ATP-binding cassette subfamily G member 2 (ABCG2), and cytochrome P450 9C9
(CYP2C9) are suggested as safety biomarkers for statins. The Clinical Pharmacogenomic Implementation
Consortium (CPIC) issued clinical guidelines fo… Show more
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