Utilizing gemstone spectral CT imaging to evaluate the therapeutic efficacy of radiofrequency ablation in lung cancer

Liu, Lei; Zhi, Xiao; Liu, Baodong; Zhang, Yi

doi:10.1007/s11547-015-0602-5

Cited by 11 publications

(4 citation statements)

References 16 publications

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“…Single energy, according to the optimization of organizational structure in contrast from another point of view, shows the organizational structure of the different components better; low energy levels are beneficial to enhance the visibility of the organizations and travel is much easier to show the opposite sex, thus improving the detection of small lesions or ingredients within the organizational structure which has the different components [24].…”

Section: E Value Of Single Energy Ct In Differentiating Benign Pleuramentioning

confidence: 99%

CAMPO Precision128 Max ENERGY Spectrum CT Combined with Multiple Parameters to Evaluate the Benign and Malignant Pleural Effusion

Zhang

et al. 2021

Journal of Healthcare Engineering

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The emergence of energy spectrum CT provides greater diagnostic value for clinical practice. Its advantage is that it can provide more functional imaging parameters and accurate image information for clinical practice, which represents a mainstream direction of CT technology development at present. This paper mainly studies the clinical trial of CAMPO Precision128 Max ENERGY spectrum CT combined with multiple parameters to evaluate the benign and malignant pleural effusion. This paper analyzes the principle and key performance parameters of energy spectrum CT imaging, the etiology of pleural effusion, and its conventional diagnostic methods and uses energy spectrum CT to detect the benign and malignant pleural effusion. In this paper, two groups of patients with different types of pleural effusions were scanned by line spectrum chest CT scans, and energy spectrum analysis software was used to measure and calculate the CT values of conventional mixed energy values of ROI of patients with pleural effusions. For the CT value and energy curve slope measurement value of different single energy keV, independent sample t-test was used to analyze and compare the two sets of data, and finally it has been found out that the two sets of data were similar. According to the experimental results, the curves of energy spectrum of the two groups of data are similar in the descending curve of bow-back. The slope of energy spectrum curve in the leakage group was lower than that in the exudate group, showing statistical significance ( P < 0.05 ). The slope of energy spectrum curve K in the malignant pleural effusion group was significantly higher than that in the benign pleural effusion group, and the difference was statistically significant ( P < 0.05 ). The trend of energy spectrum curves of the two is roughly the same, while at the high energy level, part of the energy spectrum curves of the two are overlapped. The above conclusion indicates that energy spectrum CT plays a certain role in the differential diagnosis of pleural effusion. At the same time, energy spectrum CT also provides a noninvasive and rapid examination method for clinical differentiation of pleural effusion, which has certain clinical application value and prospect.

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Section: E Value Of Single Energy Ct In Differentiating Benign Pleuramentioning

confidence: 99%

CAMPO Precision128 Max ENERGY Spectrum CT Combined with Multiple Parameters to Evaluate the Benign and Malignant Pleural Effusion

Zhang

et al. 2021

Journal of Healthcare Engineering

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“…The summary of 27 studies is listed in Table 2 [5-15, 17-22, 30, 31, 33-40]. The mean age of included studies was beyond 45.7 years, and 62.2% were males.…”

Section: Discussionmentioning

confidence: 99%

CT-guided percutaneous laser ablation of metastatic lung cancer: three cases report and literature review

et al. 2016

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ObjectiveTo report the efficacy and safety of CT-guided percutaneous laser ablation (PLA) for metastatic lung tumors.MethodsThree cases of metastatic lung cancer underwent CT-guided PLA, and we searched for previously published articles on the minimally invasive CT-guided RFA or MWA for lung tumors in recent five years.ResultsWith the guidance of CT, all lesions had good prognosis under laser ablation. Case 1 suffering from severe pulmonary dysfunction and diffuse pulmonary bullae, had small pneumothorax. CT scan obtained four months following the ablation showed two lesions had complete responses and one partial response. Case 2 had successful complete response with absent lung mass, and also had a good postoperative condition without any discomfort in the two-month follow-up. Case 3 showed partial response and improved greatly after five months. 962 cases (mean age of 45.7 years, 62.2% male) of 1297 lung tumors with detailed information were identified from 27 articles. Of these cases, the minority manifested complications such as pneumothorax, hemoptysis, hemothorax, pneumonia, pain and fever.ConclusionsPercutaneous CT-guided PLA could be a safe and promising minimally invasive treatment for patients with primary lung cancer or unresectable pulmonary metastases, especially multineedle PLA in large tumors, which still needs more large-scale prospective studies to convince this method in the future.

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“…To the best of our knowledge, this study is the first to utilize “one-stop” spectral combined perfusion scanning to demonstrate the correlation between the two imaging modalities. Although previous studies have demonstrated significant correlations between energy spectrum and perfusion parameters in liver, pancreatic, and colorectal cancers ( 21 - 23 ), the advantage of the current study was in obtaining two quantitative parameters with only one contrast injection and one scan of the patient, which reduced the amount of contrast agent and shortened the examination time ( 24 ). In addition, we employed real-time iterative reconstruction Veo algorithm to reduce radiation dose while maintaining image quality through pre- and post-processing techniques ( 25 ).…”

Section: Discussionmentioning

confidence: 98%

Can spectral computed tomography (CT) replace perfusion CT to assess the histological classification of non-small cell lung cancer?

Deng¹,

Yang²,

Jing³

et al. 2023

Quant Imaging Med Surg

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Background Non-small cell lung cancer (NSCLC) accounts for 80% of total lung cancer cases, it is necessary to distinguish the histological types of NSCLC. This study set out to investigate the correlation between spectral computed tomography (CT) and CT perfusion parameters in patients with NSCLC and to compare the differential diagnostic efficacy of these two imaging modalities for the histological classification of NSCLC. Methods A total of 62 eligible consecutive patients, including 32 with lung adenocarcinoma (LUAD) and 30 with lung squamous cell carcinoma (LUSC), who underwent “one-stop” spectral combined perfusion scan and pathologically confirmed NSCLC at Lanzhou University Second Hospital between September 2020 and December 2021 were prospectively enrolled. The spectral parameters of lesions in the arterial phase (AP) and venous phase (VP) [including iodine concentration (IC), effective atomic number (Zeff), CT 40keV , and slope of the spectral curve (K 70keV )] and perfusion parameters [blood flow (BF), blood volume (BV), surface permeability (PS), and mean transit time (MTT)] were assessed. Pearson or Spearman correlation analysis was performed to evaluate the correlation between the two imaging parameters, and the DeLong test was used to compare the diagnostic performance of the two imaging modalities. Results BV and BF were strongly correlated with spectral parameters CT 40keV , IC, Zeff, and K 70keV in the AP and VP (0.6

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Utilizing gemstone spectral CT imaging to evaluate the therapeutic efficacy of radiofrequency ablation in lung cancer

Abstract: By comparing the tumor size, water content and iodine content before and after RFA, we can visualize the morphology and metabolic states of the tumors and evaluate the therapeutic efficiency.

Cited by 11 publications

References 16 publications

CAMPO Precision128 Max ENERGY Spectrum CT Combined with Multiple Parameters to Evaluate the Benign and Malignant Pleural Effusion

CAMPO Precision128 Max ENERGY Spectrum CT Combined with Multiple Parameters to Evaluate the Benign and Malignant Pleural Effusion

CT-guided percutaneous laser ablation of metastatic lung cancer: three cases report and literature review

Can spectral computed tomography (CT) replace perfusion CT to assess the histological classification of non-small cell lung cancer?

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