Xinjiang is in northwest China and has abundant desert sand. Replacing natural sand with sand from deserts is an urgent need and could be used in making polyethylene fiber−engineered cementitious composite (PE−ECC). The interfacial bonding properties of desert sand PE−ECC (DSPE−ECC) were made using the optimal mix proportion (30% desert sand content, 2% fiber volume) and the laboratory’s previous research results. Normal sand PE−ECC (NSPE−ECC) and DSPE-ECC at different test ages (3, 7, 14, and 28 days) were subjected to uniaxial tensile tests, and a method for determining bonding properties is proposed. Scanning electron microscopy and X-ray diffraction were used to analyze the development of PE-ECC fiber and matrix and the formation of hydration products. The results indicated that the cracking loads of the DSPE-ECC at 3, 7, 14, and 28 days increased by 16.72%, 28%, 23.23%, and 10.05%, respectively. Desert sand had low water content and high water absorption, which slowed down the rate of C2S, C3S combining with water molecules to form C−S−H, and had a great influence on the bonding properties of ECC at 3 days. However, the bonding properties of DSPE−ECC were only slightly less than those of NSPE−ECC at 28 days, and the bonding properties had gradually stabilized. Therefore, the addition of desert sand enhanced the fiber/matrix’s bonding properties, and the bonding properties stablized with the increase in curing ages.