Utilizing a needle as a source of iron in synergistic dual photoredox catalytic generation of alkoxy radicals

Abstract

A visible-light mediated alkoxy radical generation is described, which allows for a structurally divergent oxidative C(sp3)-H bond functionalization. This protocol employs a photoredox/iron dual catalysis allowing for an unprecedented chemoselective...

Photo-induced 1,2-alkylarylation/cyclization of alkenes, alkyl halides and N-alkylindoles via an EDA-complex

“…15 Accordingly, numerous synthetic approaches toward that core have been developed. 16 Herein, we disclosed a new and straightforward one-pot synthesis of polysubstituted tetrahydrofurans via an EDA complex. In this reaction, halide acceptors first combined with heteroarene donors to form the EDA complex by visible light and then underwent the photocatalyzed SET from donor to acceptor to afford the alkyl radical and aryl radical cation, followed by the difunctionalization and cyclization with alkenes to generate polysubstituted tetrahydrofuran (Fig.…”

Electrochemical Deconstructive and Ring-Expansion Functionalization of Unstrained Cycloalkanols

“…Hong reported an efficient photocatalytic system for the selective construction of five- and six-membered benzyl cyclic ethers, using 2,4,6-triphenylpyrylium tetrafluoroborate (TPT) (Scheme a) . Additionally, Wallentin developed the etherification of alcohol via alkoxy radicals generated by visible light photoredox catalysis . Apart from the synthetic route to 5- and 6-membered cyclic ethers via intramolecular reactions, Floreancig and co-workers demonstrated the effectiveness of synthesizing oxygen-containing heterocycles with the use of Se 2 O 7 as catalyst via an intermolecular reaction.…”