Utilization of Preoperative Patient Factors to Predict Postoperative Vitamin D Deficiency for Patients Undergoing Gastric Bypass

Jin, Judy; Stellato, Thomas A.; Hallowell, Peter T.; Schuster, Margaret; Graf, Kristen N.; Wilhelm, Scott M.

doi:10.1007/s11605-009-0847-1

Cited by 25 publications

(26 citation statements)

References 14 publications

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“…In a study published by Johnson et al, there was a linear decrease in Vit D the longer patients were followed postoperatively, with a corresponding increase in PTH [4]. In examining predictors of postoperative Vit D deficiency, one recent study found preoperative Vit D level to be a significant factor [22]. Other studies implicate Roux limb length as a predictor.…”

Section: Resultsmentioning

confidence: 99%

Vitamin D Status of Morbidly Obese Bariatric Surgery Patients

Fish

Beverstein

Olson

et al. 2010

Journal of Surgical Research

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Section: Resultsmentioning

confidence: 99%

Vitamin D Status of Morbidly Obese Bariatric Surgery Patients

Fish

Beverstein

Olson

et al. 2010

Journal of Surgical Research

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“…The observation that obesity is associated with below-normal serum 25-hydroxyvitamin D concentrations and/or overt deficiency is not new; however, as obesity prevalence has grown, so have the number of reports in the literature regarding this phenomenon. [20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37][38] Some of the most recent information about low vitamin D status and obesity comes from studies in bariatric surgery patients, reporting low preoperative circulating levels of 25-hydroxyvitamin D. [21][22][23][24][25][26][27][33][34][35][36][37][38] In fact, a recent systematic review of 14 studies with about 1500 patients undergoing bariatric surgical procedures confirmed that obese individuals have serum 25-hydroxyvitamin D levels below 80 nmol l À1 preoperatively. 39 Other investigators have reported that body mass index (BMI) 25,26,[40][41][42][43][44][45][46] and body fat 20,45,…”

Section: Methodsmentioning

confidence: 99%

“…37 Even the RYGB, which is not considered to be a purely malabsorptive procedure, but incorporates both restrictive and malabsorptive elements, presents challenges for vitamin D repletion, given that variable characteristics such as limb length can affect absorption. 24 There are limited data on how best to treat low vitamin D status in bariatric surgery patients, and procedure-specific guidelines are unavailable. A few investigators have reported on the effects of routine vitamin D supplements using cholecalciferol doses found in standard multivitamins (200-400 IU day À1 ), 65,101 and this level of supplementation has typically been inadequate to restore serum 25-hydroxyvitamin D concentrations to normal.…”

Section: Methodsmentioning

confidence: 99%

The link between obesity and low circulating 25-hydroxyvitamin D concentrations: considerations and implications

et al. 2011

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Obesity and vitamin D deficiency have both been recognized as major public health issues worldwide, and there is growing evidence that they are related, although the cause-effect relationship remains unclear. Could obesity be contributing to low circulating 25-hydroxyvitamin D concentrations? Alternatively, could low vitamin D status predispose to obesity? In this review, the relationship between low circulating 25-hydroxyvitamin D and obesity, and possible underlying reasons from both perspectives, is presented. One potential mechanism by which obesity could contribute to low serum 25-hydroxyvitamin D is adipose sequestration of vitamin D. On the other hand, adipose tissue has both the vitamin D receptor and the ability to synthesize 1,25-dihydroxyvitamin D, and there is evidence that vitamin D may regulate adipose tissue mass, differentiation and metabolism in ways that might contribute to obesity. Of particular interest, vitamin D deficiency is common both before and after bariatric surgery, and is often difficult to treat, particularly with the more malabsorptive procedures. Additional research is needed to elucidate the complex and multifaceted factors underlying the association between low circulating 25-hydroxyvitamin D and obesity, and to identify optimal treatment approaches in obese individuals and in bariatric surgical patients both before and after surgery.

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“…Other studies have reported vitamin D deficiencies in obese patients ranging from 41% to 93.8% [6,[10][11][12][13][14][15][16][17]. This wide range may be partly due to the differences in definition of vitamin D deficiency (Table 3).…”

Section: Resultsmentioning

confidence: 98%

“…Studies in post-surgery patients have reported vitamin D deficiencies ranging from 42% to 81% [13][14][15]17,18]. However, there are differences in oral vitamin D supplementation (Table 4).…”

Section: Resultsmentioning

confidence: 99%

Vitamin D Levels in an Obese Population, before and after Bariatric Surgery

Tavares¹,

Oliveira²,

Varela³

et al. 2016

Int J Clin Nutr Diet

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Background: Obesity has been associated with vitamin D deficiency. The purpose of this study was to evaluate vitamin D status in obese patients, before and after bariatric surgery, and to examine the relationship of 25(OH)D 3 levels with anthropometric measurements and body fat. Methods: Laboratory values of 25(OH)D 3 , anthropometric measurements, body fat and demographics were retrospectively collected from 239 obese patients, 179 of whom had undergone bariatric surgery. Blood levels of 25(OH)D 3 were correlated with anthropometric measurements, body fat, and with weight loss in patients undergone bariatric surgery. Results:The prevalence of vitamin D deficiency (<15ng/mL) was 50% in the non-operative group and 33% in the bariatric surgery group. A negative association was found between 25(OH)D 3 and anthropometric measurements and body fat in both groups. Body mass index, gender and season were predictors of 25(OH)D 3 . Each body mass index increase of 1 kg/m 2 was associated with a decrease of 0.5 ng/mL in 25(OH)D 3 . In addition, it was found a positive association between 25(OH)D 3 and weight loss after bariatric surgery. Conclusion:The levels of vitamin D seem to be associated with obesity. This finding suggests the need for assessment of vitamin D status and oral vitamin D supplementation in this population.

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Utilization of Preoperative Patient Factors to Predict Postoperative Vitamin D Deficiency for Patients Undergoing Gastric Bypass

Abstract: It is important to recognize patients who are at risk for vitamin D deficiency before surgery so that early intervention could be in place to minimize further postoperative deficiency.

Cited by 25 publications

References 14 publications

Vitamin D Status of Morbidly Obese Bariatric Surgery Patients

Vitamin D Status of Morbidly Obese Bariatric Surgery Patients

The link between obesity and low circulating 25-hydroxyvitamin D concentrations: considerations and implications

Vitamin D Levels in an Obese Population, before and after Bariatric Surgery

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