China’s construction industries are rapidly increasing, and with that generation of Construction and Demolition waste is also growing, and another side industrial waste such as fly ash produced by a thermal power plant, Associated environmental issues, it is essential to utilize in any form; Studies by concrete experts have indicated the feasibility of suitably handling and recycling such waste in new concrete, mainly for basic-level applications. Non-autoclaved aerated concrete is a lightweight substance that could be used as substitute building materials; it is generally made up of raw materials such as Cement, quicklime, gypsum, sand, and expansion agent like an aluminum powder; in this study, 40% waste utilized, Construction and demolition waste (5%,10%,15%,20% ………40%) and Fly ash (35%,30%,25%,20%......0%) accordingly, while expansion agent maintained constant at 0.06%. The compressive strength of the final material checked after (7,14,21 and 28 days) respectively, obtained maximum strength after 28 days; this study goals to design a low cost, Non-autoclaved aerated concrete material and to reuse the waste produced from different sectors, mainly from the construction sector Keywords: Non-Autoclaved concrete, Lightweight concrete, Eco-friendly, Construction and Demolition waste, Fly ash