Utilization of Medical Treatments and Adherence to Antiretroviral Therapy among HIV-Positive Adults with Histories of Childhood Sexual Abuse

Meade, Christina S.; Hansen, Nathan B.; Kochman, Arlene; Sikkema, Kathleen J.

doi:10.1089/apc.2008.0210

Cited by 52 publications

(45 citation statements)

References 59 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Seven studies (Table 5) describe the impact of SAVA on healthcare utilization and cART adherence among HIV-infected women. [58][59][60][61][62][63][64] Healthcare utilization encompasses ED visits, hospitalizations, adherence to or nonuse of combination antiretroviral therapy (cART) despite medical indication for therapy, attendance at outpatient HIV clinics or nonuse of outpatient services, and use of mental health services. Depending on how healthcare utilization, substance abuse, and interpersonal violence were defined, these studies demonstrated that recent or ongoing IPV has a significant effect on healthcare decision making.…”

Section: Effect Of Sava On Healthcare Utilization and Combination Antmentioning

confidence: 99%

Substance Abuse, Violence, and HIV in Women: A Literature Review of the Syndemic

Meyer

Springer

Altice

2011

Journal of Women's Health

293

261

View full text Add to dashboard Cite

Women in the United States are increasingly affected by HIV/AIDS. The SAVA syndemic-synergistic epidemics of substance abuse, violence, and HIV/AIDS-is highly prevalent among impoverished urban women and potentially associated with poor HIV outcomes. A review of the existing literature found 45 articles that examine SAVA's impact on (1) HIV-associated risk-taking behaviors, (2) mental health, (3) healthcare utilization and medication adherence, and (4) the bidirectional relationship between violence and HIV status. Overall, results confirm the profound impact of violence and victimization and how it is intertwined with poor decision making, increased risk taking and negative health consequences, particularly in the context of substance abuse. Among current findings, there remain diverse and inconsistent definitions for substance abuse, violence, mental illness, adherence, and healthcare utilization that confound interpretation of data. Future studies require standardization and operationalization of definitions for these terms. Development and adaptation of evidencebased interventions that incorporate prevention of violence and management of victimization to target this vulnerable group of women and thereby promote better health outcomes are urgently needed.

show abstract

Section: Effect Of Sava On Healthcare Utilization and Combination Antmentioning

confidence: 99%

Substance Abuse, Violence, and HIV in Women: A Literature Review of the Syndemic

Meyer

Springer

Altice

2011

Journal of Women's Health

293

261

View full text Add to dashboard Cite

show abstract

“…6 In women with HIV, histories of abuse are quite prevalent, 8,9 and have been linked to risky sexual behaviors, HIV medication nonadherence, antiretroviral failure, and increased mortality. 2,3,8,[10][11][12][13] With highly active antiretroviral therapy (HAART), the HIV infection course has changed to that of a chronic illness. Moderate to high levels of adherence are necessary to achieve viral suppression (i.e., undetectable HIV viral load), reverse immune decline (e.g., improved CD4 + cell count), and decrease risk of morbidity and mortality.…”

mentioning

confidence: 99%

“…[25][26][27][28] A history of trauma or abuse among women with HIV has also been linked significantly to medication nonadherence, 3,11,29 as well as to antiretroviral failure and increased mortality. 2,3,8,11,13 Machtinger and colleagues 3 found that among HIV + biological and transgender women, those who reported recent trauma had over four-times the odds of antiretroviral failure in comparison to HIV + women who did not report recent trauma.…”

mentioning

confidence: 99%

Abuse and Resilience in Relation to HAART Medication Adherence and HIV Viral Load Among Women with HIV in the United States

Dale

Cohen

Weber

et al. 2014

AIDS Patient Care and STDs

114

View full text Add to dashboard Cite

Abuse is highly prevalent among HIV + women, leading to behaviors, including lower adherence to highly active antiretroviral therapy (HAART) that result in poor health outcomes. Resilience (functioning competently despite adversity) may buffer the negative effects of abuse. This study investigated how resilience interacted with abuse history in relation to HAART adherence, HIV viral load (VL), and CD4 + cell count among a convenience sample of 138 HIV + women from the Ruth M. Rothstein CORE Center/Cook County Health and Hospital Systems site of the Women's Interagency HIV Study (WIHS). Resilience was measured by the 10-item Connor-Davidson Resilience Scale (CD-RISC). HAART adherence ( ‡ 95% vs. < 95% self reported usage of prescribed medication) and current or prior sexual, physical, or emotional/domestic abuse, were reported during structured interviews. HIV viral load ( ‡ 20 vs. < 20 copies/mL) and CD4 + count (200 vs. < 200 cells/mm) were measured with blood specimens. Multiple logistic regressions, controlling for age, race, income, enrollment wave, substance use, and depressive symptoms, indicated that each unit increase in resilience was significantly associated with an increase in the odds of having ‡ 95% HAART adherence and a decrease in the odds of having a detectable viral load. Resilience-Abuse interactions showed that only among HIV + women with sexual abuse or multiple abuses did resilience significantly relate to an increase in the odds of ‡ 95% HAART adherence. Interventions to improve coping strategies that promote resilience among HIV + women may be beneficial for achieving higher HAART adherence and viral suppression.

show abstract

“…[10][11][12] Additionally, among those living with HIV, traumatic stress is associated with medication nonadherence, pain intensity, and interference of pain in daily functioning. [13][14][15] Finally, shame is a common consequence of CSA and has been associated with symptoms of posttraumatic stress disorder (PTSD). [16][17][18][19] Taken together, these findings suggest that the physical and psychological sequelae of CSA contribute to diminished HRQoL among those living with HIV.…”

mentioning

confidence: 99%

The Impact of Shame on Health-Related Quality of Life Among HIV-Positive Adults with a History of Childhood Sexual Abuse

Persons

Kershaw²,

Sikkema³

et al. 2010

AIDS Patient Care and STDs

Self Cite

View full text Add to dashboard Cite

Childhood sexual abuse is prevalent among people living with HIV, and the experience of shame is a common consequence of childhood sexual abuse and HIV infection. This study examined the role of shame in healthrelated quality of life among HIV-positive adults who have experienced childhood sexual abuse. Data from 247 HIV-infected adults with a history of childhood sexual abuse were analyzed. Hierarchical linear regression was conducted to assess the impact of shame regarding both sexual abuse and HIV infection, while controlling for demographic, clinical, and psychosocial factors. In bivariate analyses, shame regarding sexual abuse and HIV infection were each negatively associated with health-related quality of life and its components (physical wellbeing, function and global well-being, emotional and social well-being, and cognitive functioning). After controlling for demographic, clinical, and psychosocial factors, HIV-related, but not sexual abuse-related, shame remained a significant predictor of reduced health-related quality of life, explaining up to 10% of the variance in multivariable models for overall health-related quality of life, emotional, function and global, and social wellbeing and cognitive functioning over and above that of other variables entered into the model. Additionally, HIV symptoms, perceived stress, and perceived availability of social support were associated with health-related quality of life in multivariable models. Shame is an important and modifiable predictor of health-related quality of life in HIV-positive populations, and medical and mental health providers serving HIV-infected populations should be aware of the importance of shame and its impact on the well-being of their patients.

show abstract

Utilization of Medical Treatments and Adherence to Antiretroviral Therapy among HIV-Positive Adults with Histories of Childhood Sexual Abuse

Abstract: HIV is a chronic, life-threatening illness that necessitates regular and consistent medical care.

Cited by 52 publications

References 59 publications

Substance Abuse, Violence, and HIV in Women: A Literature Review of the Syndemic

Substance Abuse, Violence, and HIV in Women: A Literature Review of the Syndemic

Abuse and Resilience in Relation to HAART Medication Adherence and HIV Viral Load Among Women with HIV in the United States

The Impact of Shame on Health-Related Quality of Life Among HIV-Positive Adults with a History of Childhood Sexual Abuse

Contact Info

Product

Resources

About