Utilization of ion-pair complexation reaction for the spectrophotometric determination of milnacipran HCl as anti-depression drug in pharmaceutical formulations
Abstract:The present part aims to develop and validate a simple, rapid, cost-effective, sensitive and extractive spectrophotometric methods for the determination of anti-depression drug; milnacipran HCl in pure form and pharmaceutical formulations. The developed methods are based on the formation of ion-pair complexes between milnacipran HCl with three dyes, namely, bromocresol purple (BCP), bromophenol blue (BPB), or methyl orange (MO) in acidic buffer solutions. Different factors affecting the reaction between milnac… Show more
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