Utilization of excimer laser debulking for critical lesions unsuitable for standard renal angioplasty

Topaz, On; Polkampally, Pritam R.; Topaz, Allyne; Polkampally, Chudamani R.; Jara, Jessica; Rizk, Majid; McDowell, Kara; Feldman, George M.

doi:10.1002/lsm.20854

Cited by 14 publications

(4 citation statements)

References 25 publications

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“…A 0.9 to 1.7 TE laser catheter was used with 100% technical success. Second, Topaz et al [35] described a retrospective review of excimer laser debulking of 12 lesions unsuitable for standard renal angioplasty. The laser debulking using a 0.9 to 2 mm TE catheter was followed by renal artery stenting.…”

Section: Off-label Indicationsmentioning

confidence: 99%

Laser Uses in Noncoronary Arterial Disease

Jayet

Coscas

Heim

et al. 2019

Annals of Vascular Surgery

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Section: Off-label Indicationsmentioning

confidence: 99%

Laser Uses in Noncoronary Arterial Disease

Jayet

Coscas

Heim

et al. 2019

Annals of Vascular Surgery

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“…UV laser ablation of biological tissue has been successfully applied to the ablation of coronary artery and other vascular diseases because of its little thermal damage [1][2][3][4][5][6][7]. Louis G. Prevosti of the national heart, lung and Blood Research Institute of the United States took the lead in using the 308nm excimer UV laser to conduct the ablation experiment of femoral artery and carotid artery in dogs, and proposed that the 308nm excimer UV laser is a suitable light source for laser angioplasty [8].…”

Section: Introduction 11 Current Situation and Research Purposementioning

confidence: 99%

Experiment and research on 355nm ultraviolet laser ablation of coronary artery thrombosis

Yao

et al. 2023

Sixteenth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2023)

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To explore better ablation effects and rules, and guide clinical applications, 355nm high-peak-power pulsed laser is being used to replace the 308nm excimer laser in the ablation of coronary thrombus like tissues. It is characterized with the compact structure, low cost and high stability and its higher peak power leads to a higher ablation efficiency. The microparticle size of pig blood clot, chicken tibia clot and pig sebum clot with thrombus-like components were mainly measured after the UV laser ablation. Tissue temperature rising during ablation was also concerned. The particle sizes of blood clot and chicken tibia samples were concentrated at 0.5-1 µm and 1-5 µm, respectively, and the sebum clots became oil droplets. The channel wall of ablation was smooth, and the tissue temperature rise was less than 5°C. 355nm high-peak-power pulsed laser can be effectively applied to coronary artery thrombosis, coexisting atherosclerotic plaques and calcified tissues.

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“…In fact, this system has excellent potential to permit the accessibility to the clinical diagnosis that involves a specific biological tissue. The software system sends an electronic signal to the high potency laser to generate ablation with controlled removal of the tissue, which usually occurs in cases as, for example, cardiopathy, in order to treat obstructed coronary vessel [2,23], or urologic diseases involving acute symptoms associated to the kidney [4,24].…”

Section: Introductionmentioning

confidence: 99%

Automated diagnosis and treatment by lasers employing Raman spectroscopy and catheter with optical fibers

et al. 2011

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Raman spectroscopy is considered a very powerful tool for biochemical characterization, especially regarding biological samples. This technique allows the diagnosis of several diseases, such as cancer and atherosclerosis. In this context, the non invasive or minimally invasive character of the spectroscopic resources is an auspicious clinical advancement when compared with conventional procedures, which are associated to significant trauma and possible decrease in the quality of life of patients. Recently, the use of catheter with optical fibers associated to Raman spectroscopy has significantly minimized the invasive character of several clinical procedures. It is important to notice that this optical sensor already presents flexibility due to the employment of optical fibers to applications of lasers. Nowadays, this kind of device possesses autonomy of use and can be coupled to an optic fiber in order to permit the treatment with lasers. In this way, it is possible to develop an electronic automated optic system that achieves a diagnosis through catheter with optic fiber connected to a Raman spectrometer in order to analyze a certain organ and, considering the diagnosis obtained, to develop the adequate optical treatment can be automatically selected and applied to the respective organ. In the present work, the structure of this device will be presented with the more suitable optical techniques available to the laboratories. The minimum intervals of time involving each step of the sequence are evaluated and the efficiency of the spectroscopic system is discussed in details in agreement with the literature.

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Utilization of excimer laser debulking for critical lesions unsuitable for standard renal angioplasty

Abstract: Debulking of select renal artery stenoses with laser angioplasty followed by adjunct stenting is feasible. Further prospective, randomized studies will be required to explore the role of debulking and laser angioplasty in renal artery revascularization.

Cited by 14 publications

References 25 publications

Laser Uses in Noncoronary Arterial Disease

Laser Uses in Noncoronary Arterial Disease

Experiment and research on 355nm ultraviolet laser ablation of coronary artery thrombosis

Automated diagnosis and treatment by lasers employing Raman spectroscopy and catheter with optical fibers

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