Utilization of cone-beam CT for offline evaluation of target volume coverage during prostate image-guided radiotherapy based on bony anatomy alignment

Paluska, Petr; Hanus, Jozef; Sefrova, Jana; Rousková, Lucie; J, Grepl; Jansa, Jan; Kašaová, Linda; Hodek, Miroslav; Zouhar, Milan; Vošmik, Milan; Petera, Jiřı́

doi:10.1016/j.rpor.2012.03.003

Cited by 22 publications

(17 citation statements)

References 18 publications

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“…The only parameter, which supports fiducial usage in patients when large (10 mm) margins are used is rectal NTCP, which was increased by 4.5% without fiducial usage. To apply these results we assume no major differences in rectal filling between planning and fraction delivery, and provide patients with dietary instruction to minimize rectal distention (28).…”

Section: Discussionmentioning

confidence: 99%

Quantitative Evaluation of the Benefit of Fiducial Image-Guidance for Prostate Cancer Intensity Modulated Radiation Therapy Using Daily Dose Volume Histogram Analysis

Kašaová

Sirák

Jansa

et al. 2014

Technol Cancer Res Treat

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To quantitatively evaluate the extent to which fiducial-based image-guidance improves dose coverage of the target volume and sparing of critical organs for prostate cancer patients treated with intensity modulated radiotherapy (IMRT) and determination of planning margins by original approach of detailed daily dose volume histogram (DVH) and patient's position correction analysis. Sixty-two patients divided in two groups (clinical target volume (CTV) → planning target volume (PTV) margin 10 and 7 mm) were treated with IMRT using implanted fiducial markers. Each patient's treatment fraction was recalculated as it would have been treated without fiducial-guided positioning. For both plans (IGRT and non-IGRT), equivalent uniform doses (EUD), maximal and minimal doses for target volumes, normal tissue complication probability (NTCP), maximum and mean doses for organs at risk and the whole DVH differences were assessed. In the group with 10 mm margins, the only significant difference was worse rectal NTCP by 4.5%, but the CTV dose coverage remained at the same level.Recalculated plans with 7 mm margin could not achieve the prescribed target volume coverage, and the EUD decreased by 3.7 and 0.6 Gy for PTV and CTV, respectively. Desired CTV → PTV margin for non-IGRT plans should be no lower than 12 mm to guarantee 95% instances when delivered dose to CTV maintain as planned, for IGRT plans decrease this requirement to 2 mm. Prostate IMRT strategies involving margin reduction below 7 mm require image-guidance to maintain the planned dose coverage. Using fiducial-based imageguidance and large margins seems to be superfluous.

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Section: Discussionmentioning

confidence: 99%

Quantitative Evaluation of the Benefit of Fiducial Image-Guidance for Prostate Cancer Intensity Modulated Radiation Therapy Using Daily Dose Volume Histogram Analysis

Kašaová

Sirák

Jansa

et al. 2014

Technol Cancer Res Treat

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“…Utworzone na podstawie obrazowania CBCT skany tomograficzne porównywane są ze skanami tomograficznymi utworzonymi na tomografie komputerowym (kVCT), wykorzystywanymi w trakcie tworzenia planu leczenia [14][15][16]. Ocena zgodności anatomii przeprowadzona na podstawie porównania skanów tomograficznych umożliwia określenie rozbieżności nie tylko dla struktur kostnych, ale także dla narządów bądź też bloków tkanek miękkich poddanych napromienianiu.…”

Section: Wstępunclassified

Porównanie dwóch metod weryfikacji geometrycznej podczas radioterapii raka prostaty

Cyra

Adamczyk

Milecki

et al. 2014

Zeszyty Naukowe WCO, Letters in Oncology Science

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“…[1][2][3] An accurate patient setup is required as prescribed doses are very precisely delivered in stereotactic cone-beam computed tomography (CBCT) with a kV-source and a flat-panel detector mounted onto the gantry of the linear accelerator is mostly used for IGRT. In the past few years, studies have been published regarding CBCT performance comparisons.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of cone-beam computed tomography image quality assurance for Vero4DRT system

Miura¹,

Ozawa

Hayata³

et al. 2017

Reports of Practical Oncology & Radiotherapy

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a b s t r a c tWe report the characteristics of quality assurance (QA) image for Vero4DRT system with a kilo-voltage (kV) cone-beam computed tomography (CBCT) capability to perform imageguided radiation therapy (IGRT). To acquire a set of CBCT, the kV source is rotated either 215• clockwise (CW) (tube 1 from 5• to 220 • rotation, which leads to a loss in uniformity for image acquisition.Separations were observed for high-contrast resolution, with eight line pairs per centimeter corresponding to a gap size of 0.063 cm. For low-contrast resolution, the seventh largest hole was visible. This hole has a 4-mm diameter with 1.0% contrast level. We should check the contrast linearity compared with known value, even though it is out of range from the manufacturer manual.

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Utilization of cone-beam CT for offline evaluation of target volume coverage during prostate image-guided radiotherapy based on bony anatomy alignment

Abstract: Sufficient dose coverage of target volumes was not achieved for all patients. Reducing of safety margin is not acceptable. Initial rectal and bladder volumes cannot be considered representative for subsequent treatment.

Cited by 22 publications

References 18 publications

Quantitative Evaluation of the Benefit of Fiducial Image-Guidance for Prostate Cancer Intensity Modulated Radiation Therapy Using Daily Dose Volume Histogram Analysis

Quantitative Evaluation of the Benefit of Fiducial Image-Guidance for Prostate Cancer Intensity Modulated Radiation Therapy Using Daily Dose Volume Histogram Analysis

Porównanie dwóch metod weryfikacji geometrycznej podczas radioterapii raka prostaty

Evaluation of cone-beam computed tomography image quality assurance for Vero4DRT system

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