Utilization and Outcomes of BRCA Genetic Testing and Counseling in a National Commercially Insured Population

Randomized Noninferiority Trial of Telephone Delivery of BRCA1/2 Genetic Counseling Compared With In-Person Counseling: 1-Year Follow-Up

“…29,30,66 During our recruitment process, we observed low rates of prior counseling and testing utilization by women with a personal history of cancer (30%), providing additional evidence for low rates of accessing genetic counseling and *A noninferiority test tests that the telephone counseling mean is not worse than the in-person counseling mean (as the reference mean) by more than the prespecified noninferiority margin. However, it is estimated that less than one-third of these women receive genetic counseling.…”

“…16,22,23 One explanation for this is that urban women most interested in testing may have had access to genetic testing before the study. 66 Outcomes of telephone and in-person genetic counseling will likely be optimal when integrated into the health care system and the messages are supported and reinforced by the patient's entire health care team. Thus, the urban sample may have been biased toward women who were less interested in testing.…”

BRCA1/2 associated cancer susceptibility: a clinical overview

“…The primary reason for not getting counselling is the lack of referral by the physician who requested the testing. Women who did receive counselling reported a better level of understanding and satisfaction about their tests [38]. This result is rather surprising, contrasting relevant guidelines.…”

EMRdocumentation of physician–patient communication following genomic counseling for actionable complex disease and pharmacogenomic results

“…A number of studies have shown that genetic counseling can improve individual basic genetic knowledge , produce more accurate risk perceptions and greater perceived personal control . We found that participants in our parent chronic disease study receiving GC had enhanced objective understanding of the genetic variant risk contribution to potentially actionable complex disease reports .…”