Utilización del ciprofloxacino tópico en la otitis media crónica supurada

Ramos, Ángel; Ayudarte, F.; Miguel, I de; Cuyás, José M.; Cenjor, Carlos

doi:10.1016/s0001-6519(03)78439-8

Cited by 17 publications

(3 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A similar study was conducted by Ramos and colleagues in 2003. 23 Five treatment groups were assigned to patients with chronically discharging ears. They concluded that topical treatment with ciprofloxacin in chronic middle ear infection revealed improved results as compared with oral administration.…”

Section: Discussionmentioning

confidence: 99%

Efficacy of Empirical Therapy With Combined Ciprofloxacin Versus Topical Drops Alone in Patients With Tubotympanic Chronic Suppurative Otitis Media: A Randomized Double-Blind Controlled Trial

Onali

Bareeqa

Zia

et al. 2018

Clin Med Insights Ear Nose Throat

View full text Add to dashboard Cite

Background:One of the prevailing otologic infections in our country is chronic suppurative otitis media, especially the tubotympanic type for which various treatment protocols are followed. Usually, oral and topical antibiotics (mainly quinolones) are given alone or in combination. There is a lack of consensus as to whether topical drops alone are effective or a combined oral and systemic therapy should be prescribed. In our study, we have attempted to observe the efficacy of empirical therapy with combined ciprofloxacin versus topical drops only in patients with tubotympanic chronic suppurative otitis media for control of infection.Methodology:A total of 100 patients visiting the outpatient ENT department at our tertiary care hospital with clinically diagnosed chronic suppurative otitis media (tubotympanic type) were enrolled in our study. The study was reviewed and accepted by the ethical review committee. A detailed proforma was filled for all patients. All patients after aural toilet were subjected randomly to one of the 2 treatment methods, ie, topical ciprofloxacin ear drops plus an oral placebo or combined oral and topical ciprofloxacin. These patients were reviewed after 1 week of treatment.Results:It was observed that 48 of 50 (96%) patients responded to treatment in the group receiving topical ciprofloxacin, whereas 49 of 50 (98%) patients responded in the group receiving combined therapy. This difference was not significant. Moreover, age, sex, and duration of discharge did not have any effect on treatment. There were minimal side effects in both groups, which were also not significant and disappeared after discontinuation of treatment.Conclusions:The results of this study show that topical ciprofloxacin drops were as effective as combined oral and topical ciprofloxacin and that the addition of oral drug did not have any beneficial effect and added only to the cost of treatment.

show abstract

Section: Discussionmentioning

confidence: 99%

Efficacy of Empirical Therapy With Combined Ciprofloxacin Versus Topical Drops Alone in Patients With Tubotympanic Chronic Suppurative Otitis Media: A Randomized Double-Blind Controlled Trial

Onali

Bareeqa

Zia

et al. 2018

Clin Med Insights Ear Nose Throat

View full text Add to dashboard Cite

show abstract

“…Ramos y Cols. [19] mencionan que la administración de ciprofloxacino por vía oral asociado a la administración por vía tópica no aportó beneficio alguno frente a las vías de administración exclusivamente tópicas, con respecto a esto Brennan y Cols. [20] expresan que existe mucha incertidumbre acerca de si los antibióticos tópicos mejoran o no la resolución de la secreción del oído en los pacientes con otitis media supurativa crónica.…”

Section: Materials Y Métodounclassified

Aspectos clinicoepidemiológicos de las patologías ambulatorias del oído frecuentes en adultos

Gea¹

2020

ORL

View full text Add to dashboard Cite

Conflicto de intereses: Los autores declaran no tener conflictos de intereses Imágenes: Los autores declaran haber obtenido las imágenes con el permiso de los pacientes Política de derechos y autoarchivo: se permite el autoarchivo de la versión post-print (SHERPA/RoMEO) Licencia CC BY-NC-ND. Licencia Creative Commons Atribución-NoComercial-SinDerivar 4.0 Internacional Universidad de Salamanca. Su comercialización está sujeta al permiso del editor Ediciones Universidad de Salamanca / CC BY-NC-ND [2] Rev. ORL, 20xx, x, x, pp. xx-xx cional, así mismo se identificó que el uso significativo de antibióticos orales, más allá de la terapia tópica, no es del todo eficaz para evitar recidivas y complicaciones. PALABRAS CLAVE Epidemiologia y clínica de las patologías ambulatorias del oído; Uso de antihistamínicos; Terapia prologada con antibióticos orales y tópicos, OMC y otomicosis en adultos SUMMARY Introduction and objective: Otorhinolaryngology pathology has a high incidence in acute and chronic conditions in the ENT outpatient clinic, despite this; there are no accurate, reliable and standardized statistical data on the epidemiological profile of ambulatory otology pathologies in our setting. The objective of this study was to describe the clinical, epidemiological, treatment and follow-up characteristics of the three outpatient otological pathologies frequently diagnosed in the otorhinolaryngological consultation in our region. Method: A retrospective observational study was carried out in 312 patients with otological pathologies; the variables studied were processed through the IBM-SPSS® statistical program, applying a descriptive statistical technique. Results: The three most frequent outpatient diagnoses were: chronic otitis media in 60.6%, predominated in women with 44%; 12.8% presbycusis, in which there was no sex distinction and 12.17% otomycosis affecting women in 65.7%. They had a higher prevalence in people older than 51 years, from the urban area, without any professional training, manifesting as hearing loss, otorrhea, otalgia and otic pruritus, referred in isolation or in combination. It was evident that otomicroscopy, impedanciometry and liminal tone audiometry were the main otological techniques performed for the diagnosis. Pharmacological treatment in infectious processes was oral and otic ciprofloxacin, oral fluconazole associated clotrimazole or clioquinol otic, the prescription of loratadine was observed in 91.5% of patients with OMC, 40% in patients with presbycusis and 73.6% in patients with otomycosis. The main clinical complications were found in patients with OMC after a second evaluation, which were facial paralysis 2.1% and acquired cholesteatoma associated with chronic otomastoiditis in 0.96%. Discussion: The prevalence and involvement in terms of sex due to OMC, presbycusis and otomycosis disagrees with that obtained in other investigations although its prevalence with respect to age is similar to that reported by other researchers. Complementary diagnostic and treatment techniques are align...

show abstract

“…However, traditional TM scaffolds, including PBC films, lack antimicrobial capabilities and cannot effectively address mixed infections in cases of TM perforation. Quinolone otic solutions have been shown to be effective in treating chronic suppurative otitis media with an improvement rate ranging from 65 % to 95 % in previous trials [ [18] , [19] , [20] , [21] ]. The most commonly found pathogenic organisms in otorrhea were Staphylococcus and Pseudomona s. Although the minimal inhibitory concentration 90 for LEV against Staphylococcus and Pseudomona s was high, with values of 64 μg/mL and >64 μg/mL, respectively, the eradication rates were high, with values of 83.3 % for Staphylococcus and 88.9 % for Pseudomonas aeruginosa .…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial poly (1,4-butylene carbonate): Preparation, characterization, and potential applications as a material for tympanic membrane repair

Lv,

Wu,

Yan

et al. 2024

Heliyon

View full text Add to dashboard Cite

Utilización del ciprofloxacino tópico en la otitis media crónica supurada

Cited by 17 publications

References 11 publications

Efficacy of Empirical Therapy With Combined Ciprofloxacin Versus Topical Drops Alone in Patients With Tubotympanic Chronic Suppurative Otitis Media: A Randomized Double-Blind Controlled Trial

Efficacy of Empirical Therapy With Combined Ciprofloxacin Versus Topical Drops Alone in Patients With Tubotympanic Chronic Suppurative Otitis Media: A Randomized Double-Blind Controlled Trial

Aspectos clinicoepidemiológicos de las patologías ambulatorias del oído frecuentes en adultos

Antimicrobial poly (1,4-butylene carbonate): Preparation, characterization, and potential applications as a material for tympanic membrane repair

Contact Info

Product

Resources

About