“…Because the use of TEE is time-consuming, requires mild sedation for the patient, and has clear technical constraints, we very seldom use it during PMC. Nonetheless, it is a fact that TEE guidance has been shown to be a useful adjunct for patients with cardiothoracic deformity or when difficulties are encountered in performing transseptal puncture [23]. Successful passage through the patent foramen ovale on the first attempt demonstrates that, in this case, these two measures resulted in safer and more accurate positioning of the transseptal catheter.…”