Utility of the Nutritional Screening in Predicting Adverse Outcome of Patients With Overweight/Obesity and Acute Heart Failure

Uemura, Yoshiko; Shibata, Rei; Masuda, Arata; Katsumi, Yuta; Takemoto, Kenji; Koyasu, Masayoshi; Ishikawa, Shinya; Mitsuda, Takayuki; Murohara, Toyoaki; Watarai, Masato

doi:10.1016/j.cardfail.2020.02.005

Cited by 16 publications

(15 citation statements)

References 37 publications

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“…Categorical analysis of CONUT score on all-cause mortality Seven studies (8,9,14,18,19,20,21) provided the categorical analysis of the CONUT score. A fixed-effect model meta-analysis indicated that the pooled RR of all-cause mortality was 1•92 (95 % CI 1•58, 2•34) for the CONUT score ≥2 v. CONUT score 0-1, without significant heterogeneity (I 2 = 0 %; P = 0•601; Fig.…”

Section: Search Results and Studies Characteristicsmentioning

confidence: 99%

“…These studies were published from 2017 to 2020 and conducted in UK, Italy, Turkey, Japan, China and Taiwan. Seven studies (8,9,10,11,13,14,20,21) were retrospective designs and two (18,19) were prospective studies. The number of patients of the eligible studies ranged from 170 to 1120, with a total of 5196 heart failure patients.…”

Section: Search Results and Studies Characteristicsmentioning

confidence: 99%

“…Follow-up duration was up to 3•4 years. Regarding the methodological quality, eight studies (8,9,11,13,14,19,20,21) were grouped as high quality (see online Supplemental Table S1).…”

Section: Search Results and Studies Characteristicsmentioning

confidence: 99%

“…Seven studies (8,9,10,11,13,19,20) reported the predictive value of the CONUT score by continuous analysis. A random effect model meta-analysis indicated that the pooled RR of all-cause mortality was 1•16 (95 % CI 1•09, 1•24) for per point CONUT score increase, with significant heterogeneity (I 2 = 51•8 %; P = 0•053; Fig.…”

Section: Continuous Analysis Of Conut Score On All-cause Mortalitymentioning

confidence: 99%

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Prediction of all-cause mortality with malnutrition assessed by controlling nutritional status score in patients with heart failure: a systematic review and meta-analysis

Zhou

Zhao

et al. 2021

Public Health Nutr.

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Objective: The aim of this meta-analysis was to investigate the association between malnutrition assessed by the controlling nutritional status (CONUT) score and all-cause mortality in patients with heart failure. Design: Systematic review and meta-analysis. Settings: A comprehensively literature search of PubMed and Embase databases was performed until 30 November 2020. Studies reporting the utility of CONUT score in prediction of all-cause mortality among patients with heart failure were eligible. Patients with a CONUT score ≥2 are grouped as malnourished. Predictive values of the CONUT score were summarized by pooling the multivariable-adjusted risk ratios (RR) with 95 % CI for the malnourished v. normal nutritional status or per point CONUT score increase. Participants: Ten studies involving 5196 patients with heart failure. Results: Malnourished patients with heart failure conferred a higher risk of all-cause mortality (RR 1·92; 95 % CI 1·58, 2·34) compared with the normal nutritional status. Subgroup analysis showed the malnourished patients with heart failure had an increased risk of in-hospital mortality (RR 1·78; 95 % CI 1·29, 2·46) and follow-up mortality (RR 2·01; 95 % CI 1·58, 2·57). Moreover, per point increase in CONUT score significantly increased 16% risk of all-cause mortality during the follow-up. Conclusions: Malnutrition defined by the CONUT score is an independent predictor of all-cause mortality in patients with heart failure. Assessment of nutritional status using CONUT score would be helpful for improving risk stratification of heart failure.

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Section: Search Results and Studies Characteristicsmentioning

confidence: 99%

Section: Search Results and Studies Characteristicsmentioning

confidence: 99%

“…Follow-up duration was up to 3•4 years. Regarding the methodological quality, eight studies (8,9,11,13,14,19,20,21) were grouped as high quality (see online Supplemental Table S1).…”

Section: Search Results and Studies Characteristicsmentioning

confidence: 99%

Section: Continuous Analysis Of Conut Score On All-cause Mortalitymentioning

confidence: 99%

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Prediction of all-cause mortality with malnutrition assessed by controlling nutritional status score in patients with heart failure: a systematic review and meta-analysis

Zhou

Zhao

et al. 2021

Public Health Nutr.

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“…( 6 , 7 ) Recently, it was reported that the CONUT score was independently associated with the poor prognosis in many cardiovascular disease. ( 8 , 9 ) Recently, Restrepo and colleagues proposed a view that “pneumonia as a cardiovascular disease”. ( 10 ) Therefore, whether there is an association between the CONUT score and COVID-19 should be determined.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the nutritional status in patients with COVID-19

Wei

et al. 2020

J. Clin. Biochem. Nutr.

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COVID-19 has been a global health threat. We aimed to investigate the nutrition status of COVID-19 patients and evaluate the prognostic value of the controlling nutritional status (CONUT) score in these patients. 348 severe patients with COVID-19 were collected. Based on the CONUT score, 161 (46.3%) patients had mild malnutrition while 139 (39.9%) patients had moderate-severe malnutrition. Compared to the patients in normal and mild groups, the patients in moderate-severe group were older, more male, had higher counts of white blood cell and neutrophil as well as higher serum levels of C-reactive protein. Nearly half of patients (44.6%) in moderate-severe group developed acute cardiac injury, while 6.3% and 15.5% patients in normal and mild group, respectively. Patients with moderate-severe malnutrition exhibited a higher mortality than those patients with normal and mild malnutrition. Multivariate regression analysis showed the CONUT score was the independent predictor of death in patients with COVID-19 (odds ratio: 1.410; 95%CI: 1.089–1.825; p = 0.009). Malnutrition is significantly associated with poor outcome of COVID-19, while the prognosis of patients with normal nutrition status is relative favorable. The CONUT score independently predicts the prognosis of COVID-19 patients, which can help physicians to clarify patients with poor prognosis.

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Prognostic value of DCTA scoring system in heart failure

Zhao

Yang

et al. 2020

Herz

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Utility of the Nutritional Screening in Predicting Adverse Outcome of Patients With Overweight/Obesity and Acute Heart Failure

Cited by 16 publications

References 37 publications

Prediction of all-cause mortality with malnutrition assessed by controlling nutritional status score in patients with heart failure: a systematic review and meta-analysis

Prediction of all-cause mortality with malnutrition assessed by controlling nutritional status score in patients with heart failure: a systematic review and meta-analysis

Evaluation of the nutritional status in patients with COVID-19

Prognostic value of DCTA scoring system in heart failure

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