Utility of the ADOS-2 in children with psychiatric disorders

Colombi, Costanza; Fish, Angela; Ghaziuddin, Mohammad

doi:10.1007/s00787-019-01411-8

Cited by 13 publications

(11 citation statements)

References 16 publications

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“… 36 However, in children, there are no studies regarding the utility of the ADOS in orienting differential diagnosis between NDDs different from autism, but most concern the comorbidity between autism with other psychiatric disorders. 37 There is one study about Social Responsiveness Scale (SRS) in children with subthreshold ASD symptoms, but no alternative diagnosis has been formulated 38 As suggested by Lord et al 22 our results confirm the need for multiple sources of information during the diagnostic process. Given that a significant percentage of children with mental disorders not related to autism have been misclassified as having ASD, it is important to not interpret ADOS scale scores in an absolute and isolated way but to always integrate them with other information deriving also from the different contexts of the subject’s life (teachers, caregivers).…”

Section: Discussionsupporting

confidence: 63%

Differential Diagnosis in Children with Autistic Symptoms and Subthreshold ADOS Total Score: An Observational Study

Giacomo¹,

Craig²,

Palermo³

et al. 2021

NDT

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Background: Children with autism spectrum disorder (ASD) share some symptoms with children with other neurodevelopmental disorders (ie, intellectual disability or communication disorders or language disorders). These similarities can make difficult to obtain an accurate diagnosis, which is essential to give targeted treatments to the patients. We aim to verify in our study if children with autistic traits who undergo to Autism Diagnostic Observation Schedule had specific clinical diagnosis. Patients and Methods: We selected 73 children tested with ADOS-G or ADOS-2, for the presence of autistic symptoms. The whole sample did not reach the cut-off of ADOS and did not receive the ASD diagnosis, according to DSM-5. Results: Results of this study showed that in order of frequency and early diagnosis, communication disorders (CD), mild intellectual disability (mID) and the attention deficit hyperactivity disorders (ADHD) represent the most common final clinical diagnosis in children with autistic traits. Conclusion:Our results showed as the CD was the common diagnosis of these children and that often associated with younger age. Moreover, analyses of ADOS domains and the difference of individual items between groups did not show the capacity to differentiate between different neurodevelopmental disorders in terms of differential diagnosis, and this confirms the need for integrating multiple sources of information during the diagnostic process.

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Section: Discussionsupporting

confidence: 63%

Differential Diagnosis in Children with Autistic Symptoms and Subthreshold ADOS Total Score: An Observational Study

Giacomo¹,

Craig²,

Palermo³

et al. 2021

NDT

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“…Case group: 77 children with a diagnosis of ASD by the Children's Hospital, Zhejiang University School of Medicine from January 1 to December 31, 2021. Inclusion criteria: (1) Aged 1–3 years; (2) The diagnosis of ASD was performed independently by a developmental pediatrician and a psychiatrist using the DSM- 5 ( 20 ) in combination with the ADOS-2 ( 21 , 22 ); (3) Excluding other organic diseases, hearing disorders, neurodevelopmental disorders, genetic metabolism diseases as well as mental and psychological disorders; (4) Stable medical conditions, and not taking psychiatric or sleep related medications in the past 3 months. A total of 77 questionnaires were collected, of which 74 (62 males and 12 females) were valid.…”

Section: Methodsmentioning

confidence: 99%

Analysis of sleep problem in children aged 1–3 years with autism spectrum disorder in Zhejiang province, China

Yao

Wang

et al. 2022

Front. Psychiatry

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BackgroundHigh prevalence of sleep problems have been founded in children with Autism Spectrum Disorder (ASD), with rates ranging from 50 to 80%. We aimed to study the sleep status and the occurrence of sleep problems in children with autism spectrum disorder (ASD) aged 1–3 years, and to provide reference for guiding early comprehensive intervention for ASD children from the perspective of sleep.MethodsFrom January 1 to December 31, 2021, 74 ASD children who met the diagnostic criteria of “Diagnostic and Statistical Manual of Mental Disorders-5 (DSM-V)” served as case group while 84 typically-developing children of the same sex and age served as control group. An original Children's Sleep Habit Questionnaire was adopted to compare the sleep status of children in the two groups and to conduct statistical analysis on related factors.ResultsThe incidence of sleep problems in the case group (78.4%) was significantly higher than that in the control group (34.5%) (P < 0.001). Compared with the children in the control group, children in the case group had later bedtime (P < 0.05) and less sleep duration (P < 0.05), and required longer time to fall asleep (P < 0.001) The incidence of sleep problems in children who could fall asleep autonomously in the case group was significantly lower than that in children who needed parental help (P < 0.05). In the case group, the longer the screen exposure time, the higher the incidence of sleep problems (P < 0.05).ConclusionsThe incidence of sleep problems in ASD children aged 1–3 years is also high, mainly manifested in late bedtime, difficulty falling asleep, frequent night awakenings and less sleep duration. Both sleep patterns and screen exposure can impact their sleep. In the early comprehensive intervention of ASD children, it is necessary to pay full heed to their sleep status and take timely intervention measures in order to improve the quality of life for the ASD children and their families.

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“…У людей с полной мутацией гена наблюдаются когнитивные нарушения, эпилептические приступы, стереотипное поведение, трудности коммуникации и социального взаимодействия, высокая социальная тревожность, робость, избегание зрительного контакта, ускоренный темп речи с многочисленными повторами и запинками, а также эхолалиями, возбуждением (в 20%), гиперактивностью с дефицитом внимания, гиперчувствительность к сенсорным стимулам [12]. В зависимости от количества белка FMR1 специфический поведенческий фенотип у людей с ломкой Х-хромосомой (FXS) проявляется в разной степени.…”

Section: клиническая характеристика (оценка врача-психиатра)unclassified

“…В последние годы в США начали появляться работы, ставящие под сомнение практику обязательного использования методик «золотого стандарта» для диагностики РАС, что, по мнению N.K. Kaufman и других специалистов, позволит более точно клинически дифференцировать РАС от множества других нарушений развития и уменьшить гипердиагностику аутизма [11,12]. К клинической оценке психиатра дополнительно рекомендуется применение различных диагностических методик, в том числе высоко оцениваются традиционные психологические и нейропсихологические диагностические методики (исследование памяти, внимания, мышления и др.)…”

Section: Introductionunclassified

Diagnostic, Clinical, Psychopathological, Psychological Aspects of the Examination of Children with Autism Spectrum Disorders

Nv¹,

Koval-Zaytsev²,

Ivanov³

et al. 2021

Psychiatry

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Objective: recently, much attention has been paid to the problem of autism spectrum disorders (ASD) in childhood. Despite the abundance of psychometric approaches to the diagnosis of autism in childhood, questions remain about the validity of their use in everyday practice. In recent years, works began to appear in the United States calling into question the practice of mandatory use of the “gold standard” methods for diagnosing ASD. Russia has many years of experience in multidisciplinary cooperation of medical psychologists and clinicians in child psychiatric practice, which makes it possible to more accurately determine the depth and severity of autistic manifestations, as well as to determine the dynamics of a child’s development, which will make it possible to provide targeted effective assistance. Aim: to develop diagnostic, clinical-psychopathological, psychological approaches to the diagnosis of autism spectrum disorders in childhood.Patients and methods: the sample consists of 254 patients aged 4–17 years (average age 7.3 years) with different forms of ASD according to ICD-10 (heading F84). The patients were examined by clinical-psychopathological, clinical-dynamic, clinical-follow-up, psychological methods.Results: the study made it possible to define the profiles of six main forms of ASD from a clinical and psychological standpoint: Asperger’s syndrome (F84.5); childhood autism dysontogenetic (F84.0); childhood psychosis (F84.02); Kanner’s syndrome (F84.01), syndromic atypical autism (F84.11),and atypical childhood psychosis (F84.12).Conclusion: the results obtained are presented in a multidisciplinary aspect, which allows the most accurately diagnose one form or another of autism spectrum disorders and to develop personalized routes of patient management.

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Utility of the ADOS-2 in children with psychiatric disorders

Cited by 13 publications

References 16 publications

Differential Diagnosis in Children with Autistic Symptoms and Subthreshold ADOS Total Score: An Observational Study

Differential Diagnosis in Children with Autistic Symptoms and Subthreshold ADOS Total Score: An Observational Study

Analysis of sleep problem in children aged 1–3 years with autism spectrum disorder in Zhejiang province, China

Diagnostic, Clinical, Psychopathological, Psychological Aspects of the Examination of Children with Autism Spectrum Disorders

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