Utility of Synthetic, Medicinal and Pharmaceutical Chemistry in Drug Design

Abstract

Drug design is a creative act of the same magnitude as composing, sculpting, or writing. The results can touch the lives of millions and bring dollars of millions. Drug design, sometimes referred to as rational drug design or simply rational design, is the inventive process of finding new medications based on the knowledge of a biological target. Similarly, drug development is the process of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery. It includes pre-clinical research (microorganisms/animals) and clinical trials (on humans) and may include the step of obtaining regulatory approval to market the drug. This review helps in the development of newer molecules for future drug discovery.

Synthesis, enzyme inhibition, and molecular docking studies of a novel chalcone series bearing benzothiazole scaffold

“…The development of new drugs and pharmaceuticals is a critical and challenging issue for the researchers. Organic and medicinal chemists pursued the synthesis of newer motifs and valued their pharmacophorical qualities as a result of the extensive range of synthetic and therapeutic properties demonstrated by hybrid heterocyclic compounds 29 . The novel hybrid drug design besides enzyme inhibitors and other pharmacological agents with docking and theoretical studies have also increased as innovative approaches for the treatment of pathologies.…”