Utility of syndromic approach in management of sexually transmitted infections: public health perspective

doi:10.12980/jclm.2.20143d237

Cited by 7 publications

(7 citation statements)

References 26 publications

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“…Syndromic management is based on the identification of a combination of symptoms presented during a clinical examination (Shrivastava et al, 2014). These symptoms may be easily recognized signs associated with infection and known bacterial pathogens (Shrivastava et al, 2014). A diagnosis is made by a healthcare provider within a short time, without sophisticated skills and laboratory tests (Altini, 2006).…”

Section: Problem Of Syndromic Management In Resource-limited Settingsmentioning

confidence: 99%

“…Syndromic management of sexually transmitted infections (STIs) and BV has its benefits, especially in resource-limited settings where invasive procedures and laboratory tests are not available. These benefits include the amendment of immediate treatment on the patient's first visit to a clinic, (reducing further transmission of the disorder), it's widely accessible, education is provided, and no laboratory tests are needed (World Health Organization, 2007;Shrivastava et al, 2014). The success of syndromic management relies on accurate information including the sexual history of the patient and a thorough clinical examination (National Department of Health (South Africa), 2015).…”

Section: Problem Of Syndromic Management In Resource-limited Settingsmentioning

confidence: 99%

“…Diagnosis and effective treatment of BV in pregnant women are warranted to avoid the development of pregnancy complications as well as the acquisition of HIV and other STIs. To diagnose and treat asymptomatic BV, lowcost but sensitive and specific diagnostic models for resourcelimited countries are needed in addition to a proposed shift from syndromic to diagnostic management (Shrivastava et al, 2014;Garrett et al, 2018).…”

Section: Problem Of Syndromic Management In Resource-limited Settingsmentioning

confidence: 99%

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Bacterial Vaginosis: Current Diagnostic Avenues and Future Opportunities

Redelinghuys

Geldenhuys

Jung

et al. 2020

Front. Cell. Infect. Microbiol.

112

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A healthy female genital tract harbors a microbiome dominated by lactic acid and hydrogen peroxide producing bacteria, which provide protection against infections by maintaining a low pH. Changes in the bacterial compositions of the vaginal microbiome can lead to bacterial vaginosis (BV), which is often associated with vaginal inflammation. Bacterial vaginosis increases the risk of acquiring sexually transmitted infections (STIs) like human immunodeficiency virus (HIV) and affects women's reproductive health negatively. In pregnant women, BV can lead to chorioamnionitis and adverse pregnancy outcomes, including preterm premature rupture of the membranes and preterm birth. In order to manage BV effectively, good diagnostic procedures are required. Traditionally clinical and microscopic methods have been used to diagnose BV; however, these methods require skilled staff and time and suffer from reduced sensitivity and specificity. New diagnostics, including highly sensitive and specific point-of-care (POC) tests, treatment modalities and vaccines can be developed based on the identification of biomarkers from the growing pool of vaginal microbiome and vaginal metabolome data. In this review the current and future diagnostic avenues will be discussed.

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Section: Problem Of Syndromic Management In Resource-limited Settingsmentioning

confidence: 99%

Section: Problem Of Syndromic Management In Resource-limited Settingsmentioning

confidence: 99%

Section: Problem Of Syndromic Management In Resource-limited Settingsmentioning

confidence: 99%

See 1 more Smart Citation

Bacterial Vaginosis: Current Diagnostic Avenues and Future Opportunities

Redelinghuys

Geldenhuys

Jung

et al. 2020

Front. Cell. Infect. Microbiol.

112

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“…The causative agents include bacteria, viruses including human immunodeficiency virus (HIV), and parasites [1, 2]. STIs are important because of their magnitude, potential complications, and their interaction with HIV/AIDS.…”

Section: Introductionmentioning

confidence: 99%

Knowledge and Practice of Clinicians regarding Syndromic Management of Sexually Transmitted Infections in Public Health Facilities of Gamo Gofa Zone, South Ethiopia

Alemayehu

Godana

2015

Journal of Sexually Transmitted Diseases

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Background. Sexually Transmitted Infections (STIs) are the leading causes of morbidity among young adults. This study assessed the knowledge and practice of clinicians regarding syndromic management of STIs in public health facilities of Gamo Gofa Zone, Southern Ethiopia. Methods. Facility based cross-sectional study with mixed methods of data collection was conducted in public health facilities of Gamo Gofa Zone. The study included 250 clinicians and 12 health facilities, 26 mystery clients were hired, and 120 STI patient cards were reviewed. Data was entered in EPI info version 7.0.1 and analyzed by SPSS version 20. Results. Of the participated clinicians, 32 (12.8%) were trained on syndromic management of STIs. Highest knowledge of clinicians was for urethral discharge (27.2%). Professional category of clinicians and type of health facility (AOR = 0.194; 95% CI = 0.092, 0.412) were determinants of urethral discharge knowledge. Of the cards reviewed, only in 8.3% of cards and 19.23% of mystery clients did the clinicians correctly follow the guideline. Conclusion. Knowledge and practice of clinicians regarding syndromic management of STIs in study area were poor. Efforts should be made to increase the knowledge of clinicians by providing training on syndromic management of STIs and supportive supervision should be regular.

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“…The VDS algorithm has low sensitivity and asymptomatic infections are undetected since it solely relies on symptoms and signs. 29 Gemert et al (2018) showed that the efficacy of the VDS algorithm is inadequate for the treatment of AVD. The majority of women with cervical infections were undetected and remained untreated while uninfected women were treated unnecessarily.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Chlamydia trachomatis infection in pregnant women from Durban, South Africa

et al. 2022

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Introduction The Sub–Saharan African region has some of the world’s highest prevalence of sexually transmitted infections (STIs). These infections are considered a major public health concern. Previous studies on the prevalence of C. trachomatis infection in Sub-Saharan Africa have reported rates ranging from 3.1% to 36.8% in pregnant women. This study investigated the prevalence and risk factors associated with C. trachomatis infection in pregnant women. Methods This study included 735 stored clinical samples that were collected from pregnant women attending the antenatal clinic at King Edward VIII Hospital in Durban from 2018 -2021. C. trachomatis was detected using the Applied BiosystemsTM TaqMan® Assays from stored DNA samples. Results A total of 81/735 (11%) samples tested positive for C. trachomatis infection. The overall median (Q1-Q3) age of the women was 29.0 years (24.0–35.0). The majority of the women who tested positive for C. trachomatis were younger, median (Q1-Q3) age 26.0 years (23.0–32.0) vs 30.0 years (25.0–35.0) for the negative women ( p < .001). Of the positive women, 96.3% were unmarried ( p=0.014). Older women were less likely to test positive for C. trachomatis infection (OR: 0.93; 95% CI 0.89–0.96 p = .001). Women who were married (OR: 0.25; 95% CI 0.06–0.70; p = .022), co-habiting with their partner (OR: 0.60; 95% CI 0.36–0.98; p = .048) and started having sex at older than 15 years (OR:0.26; 95% CI 0.09–0.87; p = .018) were less likely to test positive for C. trachomatis compared to their counterparts. Conclusion This study showed that behavioural and clinical factors were associated with prevalent infections. In order to reduce prevalent infections, stronger risk reduction counselling messages need to be provided from the educational and public health sector.

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Utility of syndromic approach in management of sexually transmitted infections: public health perspective

Cited by 7 publications

References 26 publications

Bacterial Vaginosis: Current Diagnostic Avenues and Future Opportunities

Bacterial Vaginosis: Current Diagnostic Avenues and Future Opportunities

Knowledge and Practice of Clinicians regarding Syndromic Management of Sexually Transmitted Infections in Public Health Facilities of Gamo Gofa Zone, South Ethiopia

Prevalence of Chlamydia trachomatis infection in pregnant women from Durban, South Africa

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