Utility of single photon emission computed tomography–computed tomography in selective sentinel lymph node biopsy in patients with melanoma

Castillo, R. Martínez; López, Rosa Fernández; Báñez, I. Acevedo; Pérez, Rosalía Martínez; Solís, David García; Albertino, R. Vázquez; Ortega, P. Fernández

doi:10.1016/j.remnie.2014.02.013

Cited by 6 publications

(2 citation statements)

References 27 publications

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“…Hybrid single photon emission computed tomography/ computed tomography (SPECT/CT) technique combines SPECT and low-dose CT and is increasingly being used in everyday practice. Hybrid imaging with SPECT/ CT provides better anatomical landmarks due to the CT component, as well as accurate detection of additional SLNs not visualized on planar scintigraphy (PLS) [9]. Moreover, it is possible for those additional SLNs to contain metastases.…”

Section: Introductionmentioning

confidence: 99%

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The impact of sentinel lymph node mapping with hybrid single photon emission computed tomography/computed tomography in patients with melanoma. Comparison to planar radioisotopic lymphoscintigraphy

et al. 2023

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We studied the diagnostic value of 16 slices of single photon emission computed tomography (SPECT)/computed tomography (CT) in the anatomical localization, image interpretation and extra-sentinel lymph nodes (SLNs) detection compared to dynamic and static planar radioisotopic lymphoscintigraphy (PLS) in patients with melanoma. Eighty-two patients with melanoma underwent dynamic PLS, static PLS and SPECT/CT. Data were obtained using a dual head SPECT/CT 16 slices γ-camera. We evaluated the number and localization of SLNs detected with each imaging method. SPECT/CT demonstrated 48 additional SLNs in comparison with PLS in 29 patients. In five truncal and seven head-neck lesions, dynamic and static PLS failed to detect the SLNs found on SPECT/CT (false negative). In one case of truncal and one case of lower limb melanoma, the foci of increased activity interpreted on PLS as possible SLNs were confirmed to be non-nodal sites of uptake on SPECT/CT (false positive). PLS underestimated the number of SLNs detected, whereas SPECT/CT revealed higher agreement compared to the respective number from histological reports. SPECT/CT showed a better prediction of the number of SLNs and higher diagnostic parameters in comparison to planar imaging. SPECT/CT is an important complementary diagnostic modality to PLS, that improves detection, preoperative evaluation, anatomical landmarks of SLNs and surgical management of patients with melanoma.

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Section: Introductionmentioning

confidence: 99%

“…Moreover, it is possible for those additional SLNs to contain metastases. Therefore, SPECT/CT could be a promising tool for planning surgical procedures, expediting surgical management, providing accurate staging, and allowing better design of the therapeutic approach [9,10].…”

Section: Introductionmentioning

confidence: 99%