Utility of Simple and Non-Invasive Strategies Alternative to Inferior
Petrosal Sinus Sampling and Peripheral CRH Stimulation in Differential Diagnosis
of ACTH-Dependent Cushing Syndrome
Bhawna Attri,
Alpesh Goyal,
Mani Kalaivani
et al.
Abstract:We aimed to evaluate the utility of simple, cost-effective, and non-invasive strategies alternative to BIPSS and peripheral CRH stimulation in differential diagnosis of ACTH-dependent CS. We performed ROC analysis to evaluate the performance of various tests for differential diagnosis of ACTH-dependent CS in our cohort (CD, n=76 and EAS, n=23) and derived their optimal cut-offs. Subsequently, combining various demographic (gender), clinical (hypokalemia), biochemical (plasma ACTH, HDDST, peripheral CRH stimula… Show more
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