Utility of salivary biomarker for stress induced by dental treatment

Ohura, Kiyoshi; Nozaki, Tadashige; Shinohara, Mitsuko; Daito, Kiyoshi; Sonomoto, Mie; Daito, Michiharu

doi:10.1016/j.jdsr.2011.06.001

Cited by 5 publications

(4 citation statements)

References 35 publications

(37 reference statements)

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“…Moreover, salivary amylase level was observed to react more rapidly than cortisol during psychological stress, which could be a better indicator of stress 38 . However, stress during dental treatment showed significant changes in the salivary cortisol and sIgA levels than alpha-amylase 42 . During acute stress, salivary nitrate and nitrite are significantly increased which play a significant role in stress-induced gastric injury protection.…”

Section: Does Psychological Stress Make a Change In Salivary Protein mentioning

confidence: 86%

Compliance with Saliva Collection Protocol in Healthy Volunteers: Strategies for Managing Risk and Errors

2018

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Salivary bioscience technologies such as electrophoresis are widely applied for diagnosing systemic health status. Diagnosis using a saliva sample has emerged as a preferred technique since the sample is easy to collect and the method is inexpensive and non-invasive. Salivary diagnostics have even been identified as potential substitutes for serum protein biomarkers. However, the optimal protocol for collecting saliva has not yet been established. In many scientific settings, such as randomized controlled trials, sampling and statistical errors often occur when handling samples from healthy volunteers. These errors can be due to the psychological behavior of the volunteers, subject nonadherence, questionnaire characteristics, collection methods, and/or sample processing. The purpose of the review presented here is to outline the strategies for managing the risk factors and to minimize the sampling errors during saliva collection in healthy volunteers.

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Section: Does Psychological Stress Make a Change In Salivary Protein mentioning

confidence: 86%

Compliance with Saliva Collection Protocol in Healthy Volunteers: Strategies for Managing Risk and Errors

2018

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“…Mild stress can be useful for tasks and cognitive performance, while constant and high stress leads to anxiety and depression 1. When stresses occur in the body, sympathetic-adrenal-medullary (SAM) reacts through norepinephrine secretion and Hypothalamic-pituitary-adrenal (HPA) is activated by cortisol secretion 2. However, serum, urine and saliva cortisol are classical biomarkers to measure 34…”

Section: Introductionmentioning

confidence: 99%

Salivary Testosterone Levels Under Psychological Stress and Its Relationship with Rumination and Five Personality Traits in Medical Students

Afrisham

Sadegh-Nejadi

Soliemanifar

et al. 2016

Psychiatry Investig

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ObjectiveThe purpose of this study was to evaluate the salivary testosterone levels under psychological stress and its relationship with rumination and five personality traits in medical students.MethodsA total of 58 medical students, who wanted to participate in the final exam, were selected by simple random sampling. Two months before the exam, in the basal conditions, the NEO Inventory short form, and the Emotional Control Questionnaire (ECQ) were completed. Saliva samples were taken from students in both the basal conditions and under exam stress. Salivary testosterone was measured by ELISA. Data was analyzed using multivariate analysis of variance with repeated measures, paired samples t-test, Pearson correlation and stepwise regression analysis.ResultsSalivary testosterone level of men showed a significant increase under exam stress (p<0.05). However, a non-significant although substantial reduction observed in women. A significant correlation was found between extroversion (r=-0.33) and openness to experience (r=0.30) with salivary testosterone (p<0.05). Extraversion, aggression control and emotional inhibition predicted 28% of variance of salivary testosterone under stress.ConclusionSalivary testosterone reactivity to stress can be determined by sexual differences, personality traits, and emotional control variables which may decrease or increase stress effects on biological responses, especially the salivary testosterone.

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“…The fidelity of children's answers to the questionnaire is confirmed by the results of immunoglobulin A, which indicated lower values at the end of the experiment in the experimental group. Ohura et al (2012) showed that the salivary biomarker IgA indicated a significant increase in dental treatment stress compared to alpha-amylase.…”

Section: Discussionmentioning

confidence: 99%

The Role of the Educational Program in Reducing the Child's Anxiety at the Dentist

Vlad,

Mihai,

Monea

2023

ESJ

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The objective of the study was to create and implement an educational program with the aim of reducing children's anxiety at the dentist. The study began with the hypothesis that the implementation of an educational program can lead to a decrease in the level of dental anxiety among children. The sample included 196 children (experimental group of 95 children and control group of 101 children), primary school pupils. The educational program was structured in the form of twelve PowerPoint presentations, focusing on three essential themes. These were: the importance of oral hygiene, methods and techniques used for good oral hygiene and the role of nutrition in maintaining healthy teeth. The methods used were the questionnaire, PowerPoint presentations, semi-structured interviews, demonstrations and exercises. A questionnaire was applied and saliva was taken to determine immunoglobulin A, both at the beginning and at the end of the study. In the experimental group, there were statistically significant differences between the initial and final results of both the questionnaire and immunoglobulin A testing (p<0.05). There were no statistically significant differences in the control group (p>0.05). Following the interpretation of the results, the hypothesis was confirmed according to which the implementation of an educational program can lead to a decrease in the level of dental anxiety in children.

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Utility of salivary biomarker for stress induced by dental treatment

Cited by 5 publications

References 35 publications

Compliance with Saliva Collection Protocol in Healthy Volunteers: Strategies for Managing Risk and Errors

Compliance with Saliva Collection Protocol in Healthy Volunteers: Strategies for Managing Risk and Errors

Salivary Testosterone Levels Under Psychological Stress and Its Relationship with Rumination and Five Personality Traits in Medical Students

The Role of the Educational Program in Reducing the Child's Anxiety at the Dentist

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