Utility of preoperative vascular embolization of renal tumors with left renal vein tumor thrombus

Velasco, J. Caño; Pujol, L. Polanco; Amo, F. Herránz; García, Jorge; Chamizo, J. Aragón; Fernández, C. Hernández

doi:10.1016/j.acuroe.2021.02.009

Cited by 2 publications

(1 citation statement)

References 27 publications

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“…For these patients, the rate of postoperative recurrence and distant metastasis is high, even with aggressive surgical treatment, ultimately worsening the patient’s prognosis ( 13 , 14 ). When the tumor thrombus enters the blood or lymphatic vessels, vascular tumor thrombus may lead to lymph node metastasis and, also, distant metastasis ( 15 , 16 ). In pathology, a vascular tumor thrombus is used as an important biological indicator to evaluate the degree of malignancy and is an important marker of recurrence and prognosis.…”

Section: Discussionmentioning

confidence: 99%

A postoperative tumor-specific death prediction model for patients with endometrial cancer: a retrospective study

Chen,

Yan,

et al. 2024

Transl Cancer Res

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Background Endometrial cancer (EC) is an epithelial malignancy occurring in the endometrium, with a 5-year mortality rate of above 10%. However, there is currently a lack of studies exploring the potential of a predictive model of tumor-specific death after surgery in these patients. Methods From January 2015 to December 2017, data related to 482 patients with EC admitted to the Dushu Lake Hospital Affiliated to Soochow University were analyzed. Patients were divided into death (n=62) and survival (n=420) groups according to whether tumor-specific death occurred at 5 years postoperatively or not. The clinical characteristics of the two groups were compared, and the risk factors for tumor-specific death in patients with EC 5 years after surgery were investigated by logistics regression analysis. A nomogram prediction model was established according to the relevant risk factors. Results Tumor size, Ki-67 positive rate, Federation International of Gynecology and Obstetrics (FIGO) stage, and the rate of vascular tumor thrombus between the two groups (P<0.05) were found to be the statistically significant factors. Positive Ki-67, tumor size >3.35 cm, stage III, and vascular tumor thrombus were factors that influenced the tumor-specific death at 5 years after surgery (P<0.05). The predictive model obtained an area under the receiver operating characteristic (ROC) curves in the training and verification sets of 0.847 [95% confidence interval (CI): 0.779–0.916] and 0.886 (95% CI: 0.803–0.969), respectively. Conclusions The nomogram prediction model, which was established in this study, was proved to be valuable in predicting tumor-specific death 5 years after the surgery in patients with EC.

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Section: Discussionmentioning

confidence: 99%

A postoperative tumor-specific death prediction model for patients with endometrial cancer: a retrospective study

Chen,

Yan,

et al. 2024

Transl Cancer Res

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A systematic review and meta-analysis on the efficacy of preoperative renal artery embolization prior to radical nephrectomy for renal cell carcinoma: Is it necessary?

Rooseno,

Hakim,

Djojodimedjo

2023

Arch Ital Urol Androl

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Introduction: Radical nephrectomy for Renal Cell Carcinoma (RCC) is still the treatment of choice for all stages except for stage I and IV, which need patient selectivity. The purpose of Renal Artery Embolization (RAE) pre-operative before radical nephrectomy is to facilitate resection, reduce bleeding, and reduce the time to surgery, but the necessity of this procedure is still debatable. This study investigates the efficacy of pre-operative Renal Artery Embolization (PRAE) before radical nephrectomy for RCC patients. Methods: The systematic searches based on PRISMA guidelines were conducted in Pubmed, Scopus, Web of Science, Medrxiv, and ScienceDirect databases with pre-defined keywords. Both analyses, quantitative and qualitative, were performed to assess blood loss, transfusion rate, surgical time, Intensive Care Unit (ICU) stay, and hospital stay. Results: A total of 921 patients from 8 eligible studies were included. The blood loss was significantly lower in the PRAE group compared to the control group (p = < 0.00001; SMD -20 mL; 95%CI -0.29, -0.12). There is no statistically significant difference between RAE and without RAE in the transfusion rate nephrectomy (p = 0.53, OR 0.65; 95% CI 0.16, 2.57), mean operative time (p = 0.69; SMD 5.91; 95% CI -23.25, 35.07), mean length of hospital stay (p = 0.05; SMD 0.56; 95% CI 0.00, 1.12), and mean length of stay in the ICU (p = 0.45; SMD 11.61; 95% CI -18.35, 41.57) Conclusions: PRAE before radical nephrectomy significantly reduces blood loss in RCC patients but is similar in the surgical time, transfusion rate, and length of hospital stay and ICU stay.

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Utility of preoperative vascular embolization of renal tumors with left renal vein tumor thrombus

Cited by 2 publications

References 27 publications

A postoperative tumor-specific death prediction model for patients with endometrial cancer: a retrospective study

A postoperative tumor-specific death prediction model for patients with endometrial cancer: a retrospective study

A systematic review and meta-analysis on the efficacy of preoperative renal artery embolization prior to radical nephrectomy for renal cell carcinoma: Is it necessary?

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