Utility of Localized Surface Plasmon Resonance of Gold Nanoparticles for Spectrophotometric Determination of Dobutamine in Pharmaceutical Formulations

Abdel-Lateef, Mohamed A.; Gomaa, Hassanien; Darwish, Ibrahim A.

doi:10.1007/s11468-024-02331-3

Plasmonics

2024

DOI: 10.1007/s11468-024-02331-3

|View full text |Cite

Utility of Localized Surface Plasmon Resonance of Gold Nanoparticles for Spectrophotometric Determination of Dobutamine in Pharmaceutical Formulations

Mohamed A. Abdel-Lateef,

Hassanien Gomaa,

Ibrahim A. Darwish

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

One‐pot derivatization spectrofluorimetric method for detection of aspartame in sweetener commercial tablets and soft drinks: Greenness assessments of the methodology

AlSalem,

Alharbi,

Binkadem

et al. 2024

Luminescence

View full text Add to dashboard Cite

Aspartame is an artificial sweetener used in drinks and many foods. International Agency for Research on Cancer classified aspartame as possibly carcinogenic to humans (IARC Group 2B). In this study, a sensitive and selective spectrofluorimetric method was developed to detect aspartame. The method is based on switching on the fluorescence activity of aspartame upon its condensation with O‐phthalaldehyde (Roth's reaction) in the presence of 2‐mercaptoethanol. The reaction product was detected fluorometrically at λem of 438 nm after λex of 340 nm. All reaction conditions required to yield the optimal fluorescence intensity were observed and investigated. Furthermore, the approach was validated according to ICH guidelines. Upon plotting the concentrations of aspartame against their associated fluorescence intensity values, the relationship between the two variables was linear within the range of 0.5–3.0 μg/mL. Furthermore, the method was employed to analyze the quantity of aspartame in commercial packages and soft drinks with an acceptable level of recovery. In addition, the Green Solvents Selecting Tool, Complementary Green Analytical Procedure Index, and the Analytical Greenness Metric tool were used to evaluate the sustainability and the greenness of the developed methodology.

show abstract

One‐pot derivatization spectrofluorimetric method for detection of aspartame in sweetener commercial tablets and soft drinks: Greenness assessments of the methodology

AlSalem,

Alharbi,

Binkadem

et al. 2024

Luminescence

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Utility of Localized Surface Plasmon Resonance of Gold Nanoparticles for Spectrophotometric Determination of Dobutamine in Pharmaceutical Formulations

Cited by 1 publication

References 39 publications

One‐pot derivatization spectrofluorimetric method for detection of aspartame in sweetener commercial tablets and soft drinks: Greenness assessments of the methodology

One‐pot derivatization spectrofluorimetric method for detection of aspartame in sweetener commercial tablets and soft drinks: Greenness assessments of the methodology

Contact Info

Product

Resources

About