Utility of Lesion Diameter in the Clinical Diagnosis of Cutaneous Melanoma

Abbasi, Naheed R.; Yancovitz, Molly; Gutkowicz–Krusin, Dina; Panageas, Katherine S.; Mihm, Martín C.; Googe, Paul B.; King, Roy; Prieto, Víctor G.; Osman, Iman; Friedman, Robert J.; Rigel, Darrell S.; Kopf, Alfred W.; Polsky, David

doi:10.1001/archderm.144.4.469

Cited by 51 publications

(46 citation statements)

References 29 publications

(33 reference statements)

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“…Receiver operating characteristic analysis demonstrated the usefulness of the 6 mm threshold, with downward revision of the criterion to 5 mm (or lower) resulting in significant loss of specificity. 33 Several prospective studies have assessed the frequency of small melanomas. One study found that small melanomas (\6 mm) comprised 2.2% of all lesions biopsied 33 ; however, others have reported larger estimates ranging from 11.4% (#7 mm) to 22% (\5 mm).…”

Section: Use Of the Diameter (D) Criterionmentioning

confidence: 99%

Early detection of melanoma: Reviewing the ABCDEs

Tsao

Olazagasti

Cordoro

et al. 2015

Journal of the American Academy of Dermatology

159

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Section: Use Of the Diameter (D) Criterionmentioning

confidence: 99%

Early detection of melanoma: Reviewing the ABCDEs

Tsao

Olazagasti

Cordoro

et al. 2015

Journal of the American Academy of Dermatology

159

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“…On the basis of our experience in evaluating patients at the New York University School of Medicine Melanoma Cooperative Group, we found that asymmetry, border irregularity, and color variegation were consistently associated with lesion diameter greater than 6 14 the diameter guideline of larger than 6 mm remains a useful parameter for clinical diagnosis. 15 The ABCDs were thus intended to help describe a subset of melanomas, namely early, thin tumors that might otherwise be confused with benign pigmented lesions (Fig. 4).…”

Section: Basic Factors In Early Diagnosismentioning

confidence: 99%

The Evolution of Melanoma Diagnosis: 25 Years Beyond the ABCDs

Rigel

Russak

Friedman

2010

CA: A Cancer Journal for Clinicians

336

274

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Early detection of malignant melanoma remains the key factor in lowering mortality from this cancer. Recognizing the importance of this issue 25 years ago, our group at New York University published in CA: A Cancer Journal for Clinicians the mnemonic "ABCD" to facilitate the early diagnosis of melanoma. Studies have demonstrated the usefulness of this paradigm in enhancing early melanoma diagnosis as a part of clinical examinations, mass screenings, and public education programs. Approaches to melanoma diagnosis have dynamically evolved during the ensuing quarter century. In the 1990s, dermoscopy enabled the recognition of new subsurface features to differentiate between malignant and benign pigmented lesions. During the last decade, new computer-based technologies have improved diagnostic sensitivity and specificity and may result in optimizing lesion selection for biopsy and pathology review. Despite all of the advances in melanoma diagnosis, timely recognition, detection, and rapid treatment of melanoma remain critical. Although pathologic examination remains the gold standard for diagnosis, this cancer has the potential to be diagnosed through noninvasive approaches because of its cutaneous location. From the development of the ABCDs through current attempts that use complex computer algorithms and genetic markers, a clinician's ability to detect melanoma in its earliest form has been augmented. However, a "good clinical eye" is still fundamental to selecting the lesions for evaluation among the sea of those that are prevalent. As current approaches are refined and new techniques are developed, the improved ability to diagnose this cancer will hopefully enhance reaching the goal of reducing melanoma mortality. CA Cancer J Clin 2010;60:301-316.

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“…A later amendment suggested adding an E for evolving (change in size, shape, surface, colour or sensation over time) [30]. Although some state that the D-criterion hinders the early detection of melanoma [31], as melanomas may be smaller than 6 mm [32][33][34], a large study of pigmented skin lesions revealed a clear increase in the percentage of melanomas once the limit of 6 mm was exceeded, concluding that the guideline of 6 mm is indeed useful [35]. An advantage of the ABCD criteria is that it makes it easier to distinguish between typical benign naevi and melanomas.…”

Section: Clinical Decision Aids Abcd(e) Criteriamentioning

confidence: 99%