Utility of Immediate Evaluation of Endoscopic Ultrasound-Guided Transesophageal Fine Needle Aspiration of Mediastinal Lymph Nodes

Endoscopic ultrasound-guided fine-needle aspiration and Trucut biopsy in thoracic lesions: When tissue is the issue

“…It has been suggested that FNA accuracy can decrease by up to 15% when no on-site cytopathologist is present [4]. A study evaluating the accuracy of EUS-FNA of mediastinal lymph nodes in 58 patients showed that the accuracy was 100% with on-site cytopathology but dropped to 70% without [16]. This is important as at many institutions time, personnel and cost limit the availability of these services in all EUS-guided biopsies.…”

Utility of immediate cytologic diagnosis of lung masses using ultrafast Papanicolaou stain

“…For this reason it is thought that even with improvements in diagnostic accuracy as technologies progress, even greater diagnostic accuracy can be obtained with combined use of immediate cytology. Currently, immediate cytology is also being used for other organs, including the breasts, thyroid, pancreas, liver, kidney, adrenal gland, retroperitoneum, pelvic and mediastinal lymph nodes [23][24][25][26][27][28]. Aspiration and immediate cytology with radiographic guidance can be also effectively utilized prior to percutaneous or intraoperative radiofrequency ablation [29,30].…”

Endoscopic ultrasonography‐guided fine‐needle aspiration for diagnosing upper gastrointestinal submucosal lesions: A prospective study of 50 cases

“…The average number of passes per lesion during EUS-FNA was reported to be 4. 29 A major pitfall of the EUS-FNA procedure is that aspiration of normal smooth muscle cells may result in erroneous diagnosis of a benign tumor. Similarly, aggregates of spindle-shaped neoplastic cells from a mesenchymal tumor may easily be misinterpreted as originating from the muscularis propria of the bowel wall, especially if the tumor is of low cellularity.…”