Utility of fine‐needle aspiration for diagnosis of carcinoma associated with multinodular goitre

Rı́os, Antonio; Rodrı́guez, José Manuel; Galindo, P.J.; Montoya, M.J.; Tébar, Francisco Javier; Sola, Joaquı́n; Canteras, Manuel; Parrilla, Pascual

doi:10.1111/j.1365-2265.2004.02157.x

Cited by 54 publications

(56 citation statements)

References 31 publications

(43 reference statements)

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“…Although FNAB is a reliable diagnostic technique, it is not a perfect guide in decision making for operative or nonoperative treatment of multinodular goiter. 6 In patients with thyroid carcinoma, a single false-negative result of FNAB was associated with a 28-month delay in surgical treatment, and these patients had higher rates of local invasion and persistent disease. 7 False-negative results of FNAB resulted in underestimation of clinical findings associated with thyroid carcinoma.…”

Section: Commentmentioning

confidence: 99%

“…4,5 However, as many as 80% of thyroid carcinomas can be undetected at FNAB in most patients with multinodular goiter. 6 False-negative results of FNAB cause substantial delay in surgical treatment of thyroid carcinoma, leading to local invasion in some patients. 7 Current diagnostic methods may not enable detection of the malignant nature of a thyroid nodule, especially in multinodular goiter; therefore, new techniques are being investigated to improve the evaluation of thyroid nodules.…”

Section: T He Primary Indications Formentioning

confidence: 99%

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Diagnostic Value of Dynamic Contrast Medium–Enhanced Magnetic Resonance Imaging in Preoperative Detection of Thyroid Carcinoma

Tezelman

Giles²,

Tunca³

et al. 2007

Arch Surg

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Section: Commentmentioning

confidence: 99%

Section: T He Primary Indications Formentioning

confidence: 99%

Diagnostic Value of Dynamic Contrast Medium–Enhanced Magnetic Resonance Imaging in Preoperative Detection of Thyroid Carcinoma

Tezelman

Giles²,

Tunca³

et al. 2007

Arch Surg

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“…There are some studies which declare that using FNA in MNG had been unnoticed for more than 80% of carcinomas [28]. In our survey, incidental malignancy within the pathology specimen was determined in 16 patients.…”

Section: Discussionmentioning

confidence: 92%

Treatment Outcome of Total Thyroidectomy for Multinodular Goiter

Toluee

Hedayati-Emami

Barzegar-Savasari

et al. 2015

Zahedan J Res Med Sci

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Background:In cosmetic problems, compressive symptoms, toxicity and suspicion of malignancy, the best choice of multinodular goiter treatment are surgery. There are several surgical methods. Here we managed to describe the results of total thyroidectomy method for multi nodular goiter surgeries. Patients and Methods: In this cross sectional study, from January 2009 to January 2011, 101 included patients with multi nodular goiter underwent total thyroidectomy. Outcome assessment was performed for two weeks, 1 month, 2 months, 10 months and 20 months after surgery for each patient. All data were analyzed with using SPSS-19 software. Results: Of 101 included cases, with mean age of 47.1 ± 12.9 years, 10 cases were male and 91 cases were female. Bilateral gland involvement showed in 88.11%. The fine needle aspiration results were negative for malignancy in 41.6% of patients and were indeterminate and suspicious in 53.5% and 5% of cases. Transient recurrent laryngeal nerve palsy was observed in only one case. Transient hypocalcaemia showed up in 25 patients. Incidental malignancy was determined in 15.84% of patients: one patient with medullary carcinoma, two cases with folicullar carcinoma and 13 patients with papillary carcinoma. All these cases were female and had been presented bilateral involvement of multi nodular goiter. No recurrence appeared. Conclusions: We believe that, despite the higher rate of post-operative complications, total thyroidectomy will be more beneficial in the surgical treatment of benign thyroid disorders.

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“…The usefulness of FNA in multi-nodular goiter is controversial. Recently, Antonio Rios et al [15] reported that FNA is not useful for differentiating MNG with malignant degeneration from benign MNG, as more than 80 % of carcinomas go unnoticed. Al-Yaarubi et al [16] mentioned that sensibility and specificity of FNA in determination of malignancy in MNG cases are 16 and 97 %.…”

Section: Discussionmentioning

confidence: 99%

Comparison of the results of total thyroidectomy and Dunhill operation in surgical treatment of multinodular goiter

et al. 2015

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Multi-nodular goiter (MNG) is one of the commonest thyroid gland disease. Surgery is an important treatment option in the presence of indications. There are several alternative procedures for thyroid gland operation such as subtotal thyroidectomy (STT), near-total thyroidectomy (NTT), hemi-thyroidectomy plus subtotal resection (Dunhill procedure), and total thyroidectomy (TT), but the surgical procedure of choice is still under discussion. In this study, 173 consecutive patients with multi-nodular goiter underwent thyroid operation in the department of surgery of Pursina Hospital in Rasht-Iran, using two different methods: Dunhill operation and total thyroidectomy. Outcome assessment was performed 4 days after surgery, 2 weeks, 1, 2, 10, and 20 month after surgery. Preoperative assessment, seroma, recurrent laryngeal nerve palsy, hypocalcaemia rates, and rates of other postoperative complications, final pathology, and recurrence were compared in two methods. Due to the high incidence of malignancy in this survey, TT can be the method of choice for MNG surgery. Also, TT will be more beneficial in the surgical treatment of benign thyroid disorders, especially those which are bilateral or extended to substernal space or which presented with compression symptoms.

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Utility of fine‐needle aspiration for diagnosis of carcinoma associated with multinodular goitre

Cited by 54 publications

References 31 publications

Diagnostic Value of Dynamic Contrast Medium–Enhanced Magnetic Resonance Imaging in Preoperative Detection of Thyroid Carcinoma

Diagnostic Value of Dynamic Contrast Medium–Enhanced Magnetic Resonance Imaging in Preoperative Detection of Thyroid Carcinoma

Treatment Outcome of Total Thyroidectomy for Multinodular Goiter

Comparison of the results of total thyroidectomy and Dunhill operation in surgical treatment of multinodular goiter

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