Utility of fiber-optic bronchoscopy in pulmonary infections among abdominal solid-organ transplant patients: A comprehensive review

Sakpal, Sujit Vijay; Donahue, Steven; Crespo, Hector Saucedo; Auvenshine, Christopher; Agarwal, Suresh; Nazir, Jawad; Santella, Robert N.; Steers, Jeffery L.

doi:10.1016/j.rmed.2018.12.002

Cited by 4 publications

(3 citation statements)

References 28 publications

(69 reference statements)

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“…The epidemiology of these complications is outside of the scope of this paper but some of the factors that determine the most likely diagnoses include the type of transplant, degree of immunosuppression and time since transplant (34). The overall diagnostic rate of bronchoscopy for patients with solid organ transplant and pulmonary disease is between 27-70% (35). When performed in conjunction with BAL, TBB yield a higher diagnostic rate in this population (11).…”

Section: Solid Organ Transplant Recipientsmentioning

confidence: 99%

The utility of bronchoscopy in immunocompromised patients: a review

Morton¹,

Puchalski²

2019

J Thorac Dis

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Bronchoscopy is an important tool for the diagnosis of pulmonary disorders in immunocompromised patients. The addition of biopsies to bronchoalveolar lavage improves the diagnostic yield of non-infectious etiologies, although the underlying etiology of the immunocompromised state must be considered and may be influential. Certain unknowns remain, including timing of bronchoscopy and its impact on medical management and mortality. The ongoing role of non-invasive testing for infectious complications prior to bronchoscopy also remains to be defined. This review addresses the role of bronchoscopy in immunocompromised states related to underlying hematologic malignancies, prescription drug use or chemotherapy, and other disorders that predispose patients to infectious or non-infectious pulmonary diseases.

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Section: Solid Organ Transplant Recipientsmentioning

confidence: 99%

The utility of bronchoscopy in immunocompromised patients: a review

Morton¹,

Puchalski²

2019

J Thorac Dis

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“…With the advancement of in vitro life support technology, more LT recipients are admitted to the ICU to successfully get through the perioperative period. Thus, hospitalacquired infections (HAIs) have attracted more attention in recent years (24). Bacterial infections account for approximately 36% of all secondary infectious diseases, followed by fungal infection (12%) and cytomegalovirus infection (11%) (25).…”

Section: Discussionmentioning

confidence: 99%

A bibliometric analysis of infectious diseases in patients with liver transplantation in the last decade

Zhong¹,

Liu²,

Dai³

et al. 2021

Ann Transl Med

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Background: A bibliometric analysis was performed to reveal the current status of investigations in infectious diseases in patients with liver transplantation (LT) and to prioritize future research needs. Methods:The present study comprehensively retrieved publications relevant to infectious diseases in LT recipients published between 2010 and 2020. The search was conducted on the Web of Science (WoS) database. A bibliometric analysis was conducted through machine learning and visualization tools, including VOSviewer, Bibliographic Item Co-Occurrence Matrix Builder, and Graphical Clustering Toolkit. Research hotspots and trends in the field were assessed, while the contributions and collaborations of countries, institutions, and authors were documented.Results: A total of 691 publications were analyzed. Research output sharply increased in 2015, with a fast drop afterward. "Liver transplantation" was the most frequent keyword, with strong links to "hepatitis C virus" and "infection". Study areas included risk factors of infectious diseases in LT recipients, pathogens causing post-transplantation infections, antibacterial therapy and prophylaxis for peritransplant infection complications, living donor LT, and pediatric LT. The efficacy and safety of direct-acting antivirals (DAAs) for hepatitis C virus (HCV) infection among liver transplant recipients has attracted recent research interest.Didier Samuel was the most productive author, while Xavier Forns was the top-cited author. Shanghai Jiao Tong University was the most productive contributor, and Gilead Sciences was the most cited organization.Moreover, the USA was the greatest contributor. Gastroenterology was the most cited journal, while Liver Transplantation was the most prolific journal.Conclusions: This bibliometric analysis will better understand the research status of infectious complications in LT recipients and forecast future research trends. Priority should be given to identifying risk factors for peritransplantation infections and effective treatments against infectious complications in the coming years.

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“…There is no one cause of effusion. Transudative pleural effusions and exudative pleural effusions are the two main subtypes recognised by most categorization systems [1,2] . When pleural fluid production surpasses pleural fluid drainage, pleural effusions develop.…”

Section: Introductionmentioning

confidence: 99%