Utility of cardiac MRI in the assessment of myocardial viability: Evaluating its role using 3-T machine in correlation with SPECT

Abdelrahman, Sherif Fathy; Ali, Mohamed T.; Salem, Mohamed; Sabri, Sherif

doi:10.1016/j.ejrnm.2015.10.003

Cited by 4 publications

(6 citation statements)

References 13 publications

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“…Sixteen (16) studies published between 1995 and 2016 met the inclusion criteria and were included in this meta-analysis [67][68][69][70][71][72][73][74][75][76][77][78][79][80][81][82]. The total study sample was 862 patients diagnosed with ICM (Mean = 62 years; male 70%) generating a total of 7,417 myocardial segments that were assessed.…”

Section: Study Characteristicsmentioning

confidence: 99%

“…The studies demonstrate the current ICM diagnostic methods have a high specificity (Mean = 86%) and sensitivity (Mean = 86%). Most of the studies assessed more than one diagnostic modality but the most common was myocardial perfusion -SPECT or PETassessed by nine (56%) of the studies [67,[69][70][71][72][73]75,79,81] followed by late gadolinium enhancement (LGE) cardiac MRI (LGE-MRI) assessed by 31% of the studies [69][70][71][72][73]. Two studies, 12% examined multidetector CT [82] and the other assessed Doppler echocardiography [73].…”

Section: Study Characteristicsmentioning

confidence: 99%

“…Pharmacologic stress testing in CMRI using Dobutamine was common in 38% of the studies [67,68,74,75,76,78]. All CMRI studies used 1.5T Philips or Siemens except one [81] that used Philips 3T.…”

Section: Study Characteristicsmentioning

confidence: 99%

“…Compared to myocardial perfusion considered the gold standard in the detection of hibernating myocardium, CMRI has been shown to have a high diagnostic accuracy in visualizing significant coronary stenosis and viable and non-viable myocardium [78][79][80]. CMRI using 3T is able to detect more non-viable segments comrade to SPECT [81]. Using LGE, CMRI is able to detect the location and extent of transmural scars, and distinguish normal myocardium from sub-endocardial and transmural infarcts [69,70,72,73] with close agreement to PET [71].…”

Section: Study Outcomesmentioning

confidence: 99%

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Ischemic cardiomyopathy: A review of literature on clinical status and meta-analysis of diagnostic and clinical management

Albakri¹

2018

Biol Eng Med

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Ischemic heart disease is the leading cause of sudden cardiac death. It may lead to cardiomyopathy in the setting of coronary artery disease and gradually progressing to heart failure. While ischemic cardiomyopathy is a well-recognized disease entity, the current classification systems of cardiomyopathy exclude cardiomyopathies secondary to ischemia. Further, research on ischemic cardiomyopathy is extensively fragmented, which has undermined both research consensus and comprehensive understanding. The fragmentation is attributable to its variable terminologies (ischemic heart disease or its three leading non-fatal sequela -angina pectoris, acute myocardial infarction and ischemic heart failure). Therefore, the purpose of the present review is to accumulate research on ischemic cardiomyopathy to produce a comprehensive understanding of its clinical status, diagnosis, clinical management and improve survival.

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Section: Study Characteristicsmentioning

confidence: 99%

Section: Study Characteristicsmentioning

confidence: 99%

Section: Study Characteristicsmentioning

confidence: 99%

Section: Study Outcomesmentioning

confidence: 99%

See 2 more Smart Citations

Ischemic cardiomyopathy: A review of literature on clinical status and meta-analysis of diagnostic and clinical management

Albakri¹

2018

Biol Eng Med

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“…Given the patients extensive coronary artery disease history we opted for CMR, which can further differentiate subendocardial infarction versus transmural infarction (figure 5). 12 13 Viability study with CMR can precisely delineate true aneurysm versus pseudoaneurysm. The wall of true aneurysm is made up of infarcted myocardium versus pseudoaneurysm which is composed of pericardium only.…”

Section: Discussionmentioning

confidence: 99%

Unusual presentation of left ventricular rupture

et al. 2020

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We describe a case of 49-year-old man who presented with chest pain and was diagnosed with non-ST elevation myocardial infarction. Transthoracic echocardiogram (TTE) showed severe global hypokinesis of left ventricle with ejection fraction of 25%–30%. Left heart catheterisation showed severe right coronary stenosis and focal 60%–70% distal left anterior descending artery stenosis. Cardiac MRI (CMR) was done for evaluation of viability which showed a large pseudoaneurysm which was missed on TTE and left ventriculogram. Our case demonstrates the increasing importance of cardiac MRI in the diagnosis of left ventricular pseudoaneurysm. In our case left ventricular pseudoaneurysm was missed on TTE and left ventriculogram. It was diagnosed on CMR which was ordered for evaluation of myocardium viability.

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The recent advances, drawbacks, and the future directions of CMRI in the diagnosis of IHD

Fagiry

Abdelaziz

Davidson

et al. 2021

Sci Rep

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Ischemic heart disease (IHD), also known as coronary artery disease (CAD), is a leading cause of morbidity and mortality in adults. The aims of this research were to study the recent advances on the prognostic and diagnostic value, drawbacks, and the future directions of cardiac magnetic resonance imaging (CMRI) in the diagnosis of IHD. One hundred patients with IHD who had been clinically diagnosed were enrolled in this study prospectively. CMRI; Siemens Magnetom Sola 1.5 T MRI scanner was used to examine the patients. To confirm the diagnosis, conventional coronary angiography was used. CMRI revealed that the left ventricular (LV) volumes and systolic function of male and female patients differed by age decile were 28.9 ± 3.5%; 32 ± 1.7%, 53.3 ± 11.2; 58 ± 6.6 ml, 100.6 ± 7.1; 98.3 ± 14.7 bpm, 5.4 ± 1.4; 5.8 ± 1.5 L/min, 189 ± 14.3; 180 ± 10.9 ml, and 136 ± 3.1; 123 ± 4.4 ml for the left ventricle ejection fraction (LVEF), stroke volume (SV), heart rate, cardiac output, end diastolic volume (EDV), and end systolic volume (ESV), respectively. CMRI has sensitivity, specificity, and accuracy of 97%, 33.33%, and 95.15%, respectively. Finally, CMRI provides a comprehensive assessment of LV function, myocardial perfusion, and viability, as well as coronary anatomy.

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Utility of cardiac MRI in the assessment of myocardial viability: Evaluating its role using 3-T machine in correlation with SPECT

Cited by 4 publications

References 13 publications

Ischemic cardiomyopathy: A review of literature on clinical status and meta-analysis of diagnostic and clinical management

Ischemic cardiomyopathy: A review of literature on clinical status and meta-analysis of diagnostic and clinical management

Unusual presentation of left ventricular rupture

The recent advances, drawbacks, and the future directions of CMRI in the diagnosis of IHD

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