Utility of Anterior Segment OCT in the Management of Uveitic Cataract Surgery: A Fibrinoid Syndrome Case Treated with rtPA

Muñoz-Solano, Javier; Tondini, Giovanni; Zicarelli, Federico; Staurenghi, Giovanni; Oldani, Marta; Invernizzi, Alessandro

doi:10.1080/09273948.2023.2203232

Cited by 1 publication

(1 citation statement)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…33 Since it plays a key role in fibrinolysis, intracameral recombinant tissue plasminogen activator (rtPA) has been proposed as a possible strategy for management of severe fibrin reaction. [33][34][35][36] Rocha Lima et al described a case of severe fibrin effusion after phacoemulsification treated with intracameral injection of rtPA (25 µg/0.05 cc), showing complete dissolution of fibrin within 30 min. 33 These results are in agreement with reports from Mehta et al, showing effectivity and safety of rtPA at a dose of 25 µg for treating fibrinous membranes following paediatric cataract extraction.…”

Section: Discussionmentioning

confidence: 99%

Double trouble in DMEK surgery: Learning experience and review of the literature

Romano,

Passaro,

Airaldi

et al. 2024

European Journal of Ophthalmology

View full text Add to dashboard Cite

Purpose To report a challenging Descemet Membrane Endothelial Keratoplasty (DMEK) case, complicated by intraoperative aqueous misdirection and spontaneous anterior chamber fibrin reaction. Methods A 70-year-old female affected by corneal edema due to Fuchs endothelial dystrophy underwent a triple procedure (cataract extraction - IOL implantation - DMEK surgery) in her left eye. This report illustrates the management of the intraoperative complications of aqueous misdirection syndrome and anterior chamber fibrin reaction. Results Despite the optimal management of the posterior pressure and the thorough removal of the fibrinous reaction during the case, the DMEK graft was not completely unfolded and centred at the end of the surgical procedure. Nonetheless, the patient showed good long-term anatomical and functional recovery: at the last follow-up (2 years after surgery), central corneal thickness was 526 µm with a best corrected visual acuity of 20/25 and an endothelial cell density of 1112 cell/mm2. Conclusion Early recognition and prompt management of intraoperative aqueous misdirection syndrome and anterior chamber fibrin reaction during DMEK surgery is essential to ensure good functional and anatomical outcomes.

show abstract