“…Further, these investigators 7 were not able to include in their review an earlier 2007 study we reported, 10 as our results were presented graphically (as ROC curve analyses) without providing the numerical data needed for inclusion in the systematic review. This likely also explains why our joint Hamilton/Greifswald PIFA evaluation (assessing 289 samples, including 25 HIT-positive patients) 10 was not included in a later systematic review of rapid immunoassays by Nagler et al 8 In the meantime, additional data on the PIFA has become available, [12][13][14][15] including two studies 13,14 presented in abstract form at the recent ASH annual meeting (December 2019). We now report the results of our analysis involving the sensitivity and specificity of the PIFA in all English language studies reported to date, [10][11][12][13][14][15] along with a recent study evaluating a modified PIFA, the PIFA PLUSS.…”