Utilities for Type 2 Diabetes Treatment-Related Attributes in a South Korean and Taiwanese Population

Rajan, Narayan; Boye, Kristina S.; Gibbs, Meaghan; Lee, Yoon Ji; Davey, Peter; Ball, Mark; Babineaux, S.M.

doi:10.1016/j.vhri.2015.11.006

Cited by 11 publications

(16 citation statements)

References 45 publications

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“…The prevalence of diabetes has also increased from around nine to 11% between 2011 and 2013 in South Korea, which is alarming because diabetes and its related complications often increase the burden individuals and health care systems experience in terms of health outcomes and costs [2, 3]. In fact, previous studies have reported that diabetes act to decrease the health-related quality of life (HRQoL) of affected individuals [4]. Furthermore, diabetes and its related complications are a leading cause of morbidity and mortality in Korea [5].…”

Section: Introductionmentioning

confidence: 99%

Implementation of the Chronic Disease Care System and its association with health care costs and continuity of care in Korean adults with type 2 diabetes mellitus

Kim

Choy

Lee

et al. 2018

BMC Health Serv Res

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BackgroundThe Chronic Disease Care System (CDCS) has been implemented in Korea to encourage treatment continuity in chronic disease patients. This study investigated the effect of the introduction of the CDCS on health care costs and continuity of care in individuals with type 2 diabetes mellitus (T2DM).MethodsThe National Health Insurance data from August, 2010 to March, 2012 (pre-policy) and from May, 2012 to December, 2013 (post-policy) were used. Introduction of the CDCS was defined as the intervention. The intervention group consisted of T2DM patients participating in the program and the control group patients not participating in the program. The Difference-in-Differences (DID) method was used to estimate the differences in total health care costs for outpatient services and continuity of care between the intervention and the control group before and after the intervention period.ResultsImplementation of the CDCS was associated with decreased health care costs (β = − 46,877 Korean Won, P < 0.0001) and improved continuity of care (β = 0.0536, P < 0.0001) in the intervention group with adjustment for covariates.ConclusionFindings confirm an association between the adoption of the CDCS and reduced health care costs and improved continuity of care. The results reveal the potential benefits of reinforcing effective chronic disease management strategies in reducing health care costs and improving treatment continuity.

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Section: Introductionmentioning

confidence: 99%

Implementation of the Chronic Disease Care System and its association with health care costs and continuity of care in Korean adults with type 2 diabetes mellitus

Kim

Choy

Lee

et al. 2018

BMC Health Serv Res

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“…Of these, a total of 39 presented findings exclusively related to acute or long-term diabetes-related complications, 15 presented findings exclusively related to the influence of treatment-related attributes on QoL and 15 captured findings on both complications and treatment attributes. Therefore, a total of 30 articles presented utility/disutility values associated with treatment-related attributes or process characteristics ( Table 1 ) 7–36 These included a total of fifteen conducted in Europe, 9–11 , 13–15 , 19–21 , 24 , 25 , 29 , 31 , 33 , 34 eight conducted in Asia, 12 , 17 , 18 , 23 , 27 , 28 , 32 , 35 two in North America, 16 , 36 one in Latin America, 30 one in the Middle East, 8 one in Africa, 7 and two were multinational or the setting was not stated. 22 , 26 Most studies were conducted in people with T2D although three were conducted in general population samples 24 , 28 , 33 and one included both general population groups and groups with T2D.…”

Section: Resultsmentioning

confidence: 99%

“…Therefore, a total of 30 articles presented utility/disutility values associated with treatment-related attributes or process characteristics ( Table 1 ) 7–36 These included a total of fifteen conducted in Europe, 9–11 , 13–15 , 19–21 , 24 , 25 , 29 , 31 , 33 , 34 eight conducted in Asia, 12 , 17 , 18 , 23 , 27 , 28 , 32 , 35 two in North America, 16 , 36 one in Latin America, 30 one in the Middle East, 8 one in Africa, 7 and two were multinational or the setting was not stated. 22 , 26 Most studies were conducted in people with T2D although three were conducted in general population samples 24 , 28 , 33 and one included both general population groups and groups with T2D. 29 The most frequently used elicitation method was the EQ-5D (3L or 5L), which was used in fourteen studies, 8 , 12–15 , 18 , 22 , 23 , 25 , 27 , 30 , 32 , 34 , 36 followed by TTO methodology used in ten studies, 10 , 11 , 16 , 19–21 , 24 , 26 , 29 , 33 then the Short Form 6 Dimensions questionnaire (SF-6D; three studies), 15 , 31 , 35 SG (three studies), 9 , 17 , 28 Health Utilities Index-...…”

Section: Resultsmentioning

confidence: 99%

Evaluating the Impact of Therapy on Quality of Life in Type 2 Diabetes: A Literature Review of Utilities Associated with Treatment-Related Attributes

Valentine¹,

Norrbacka²,

Boye³

2022

PROM

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Introduction Treatment-related attributes and process characteristics such as dosing frequency, timing flexibility, ease of use of injection devices and unpleasant side-effects may have small but measurable effects on quality of life (QoL) in people with type 2 diabetes (T2D). A literature review was performed to identify recently published utility values quantifying the effect of treatment-related attributes on QoL. Methods Literature search strategies were designed using high-level medical subject heading (MeSH) terms supplemented with free-text terms and searches were run in March 2020 in the PubMed, Embase and Cochrane Library databases. For inclusion, studies were required to be published in full-text form, in English, since 2010 and report utility values (elicited using either direct or indirect methods) for treatment-related attributes or process characteristics including side effects, change in weight/body mass index (BMI), dosing frequency and timing flexibility, device attributes (e.g. needle handling, requirement for reconstitution) and convenience (e.g. waiting time). Results A total of 30 studies were included in the review, of which all but three were conducted in people with T2D. The EQ-5D was the most commonly used elicitation method (fourteen studies), followed by time tradeoff (TTO) methodology. Treatment-related adverse events and inconveniences such as needle handling in administration devices and waiting time were consistently associated with lower QoL, whereas lower dosing frequency and increased timing flexibility with dosing were consistently associated with utility benefits. The relationship between change in BMI and QoL was non-linear and influenced by baseline BMI. Conclusion Treatment-related attributes and process characteristics are associated with minor changes in QoL, which should be taken into account in long-term health economic modeling of new treatments and administration devices.

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“…[45][46][47][48] These "process utilities" quantify the impact of attributes such as mode of administration, dose frequency, medical device attributes, and aspects of treatment convenience that may have an impact on patients' quality of life. 16,17,23,[49][50][51][52][53][54][55][56][57] Treatment process usually has less impact on utility than efficacy, safety, or symptom severity, 43 but it is often important to patients. Furthermore, treatment process could affect treatment adherence, which can influence outcomes.…”

Section: Treatment Process Utilitiesmentioning

confidence: 99%

Vignette-Based Utilities: Usefulness, Limitations, and Methodological Recommendations

et al. 2021

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Health technology assessment agencies often prefer that utilities used to calculate quality-adjusted life years in cost-utility analyses (CUAs) are derived using standardized methods, such as generic preference-based measures completed by patients in clinical trials. However, there are situations when no standardized approach is feasible or appropriate for a specific medical condition or treatment that must be represented in a CUA. When this occurs, vignette-based methods are often used to estimate utilities. A vignette (sometimes called a "scenario," "health state description," "health state vignette," or "health state") is a description of a health state that is valued in a preference elicitation task to obtain a utility estimate. This method is sometimes the only feasible way to estimate utilities representing a concept that is important for a CUA. Consequently, vignette-based studies continue to be conducted and published, with the resulting utilities used in economic models to inform decision making about healthcare resource allocation. Despite the potential impact of vignette-based utilities on medical decision making, there is no published guidance or review of this methodology. This article provides recommendations for researchers, health technology assessment reviewers, and policymakers who may be deciding whether to use vignette-based methods, designing a vignette study, using vignette-based utilities in a CUA, or evaluating a CUA that includes vignette-based utilities. Recommendations are provided on: (A) when to use vignette-based utilities, (B) methods for developing vignettes, (C) valuing vignettes, (D) use of vignette-based utilities in models, and (E) limitations of vignette methods.

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Utilities for Type 2 Diabetes Treatment-Related Attributes in a South Korean and Taiwanese Population

Cited by 11 publications

References 45 publications

Implementation of the Chronic Disease Care System and its association with health care costs and continuity of care in Korean adults with type 2 diabetes mellitus

Implementation of the Chronic Disease Care System and its association with health care costs and continuity of care in Korean adults with type 2 diabetes mellitus

Evaluating the Impact of Therapy on Quality of Life in Type 2 Diabetes: A Literature Review of Utilities Associated with Treatment-Related Attributes

Vignette-Based Utilities: Usefulness, Limitations, and Methodological Recommendations

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