Utilisation du Diprivan® pour les endoscopies digestives

Meisel, M.

doi:10.1016/s0750-7658(05)80703-8

Cited by 6 publications

(4 citation statements)

References 27 publications

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“…A standardized regimen consisting of a loading dose of 1.0 mg.kg −1 followed by intermittent boluses of 0.5 mg.kg −1 has been recommended for sedation in colonoscopy. 21 According to our pharmacokinetic simulations in Tivatrainer® software, this protocol leads to peak concentrations at the effect site of 3 to 4 μg.ml −1 , which are close to the mean values observed for loss of consciousness in the experimental group of our study.…”

Section: Discussionsupporting

confidence: 82%

Safety and efficacy of target-controlled infusion versus intermittent bolus administration of propofol for sedation in colonoscopy: a randomized controlled trial

Cuiabano

Garbin²,

Módolo³

et al. 2023

Brazilian Journal of Anesthesiology (English Edition)

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Section: Discussionsupporting

confidence: 82%

Safety and efficacy of target-controlled infusion versus intermittent bolus administration of propofol for sedation in colonoscopy: a randomized controlled trial

Cuiabano

Garbin²,

Módolo³

et al. 2023

Brazilian Journal of Anesthesiology (English Edition)

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“…Propofol is a new i.v. anesthetic that has come into use in recent years . Quality of recovery is excellent, and nausea or vomiting rarely occurs.…”

Section: Drugs Used For Sedation In Gastroenterological Endoscopy Andmentioning

confidence: 99%

“…anesthetic that has come into use in recent years. 75 Quality of recovery is excellent, and nausea or vomiting rarely occurs. Although this drug is mainly metabolized in the liver, the metabolizing enzyme also exists in the kidneys and lungs, which enables an excellent recovery.…”

Section: Propofolmentioning

confidence: 99%

Guidelines for sedation in gastroenterological endoscopy

Obara

Haruma

Irisawa

et al. 2015

Digestive Endoscopy

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Recently, the need for sedation in gastrointestinal endoscopy has been increasing. However, the National Health Insurance Drug Price list in Japan does not include any drug specifically used for the sedation. Although benzodiazepines are the main medication, their use in cases of gastrointestinal endoscopy has not been approved. This has led the Japan Gastrointestinal Endoscopy Society to develop the first set of guidelines for sedation in gastrointestinal endoscopy on the basis of evidence‐based medicine in collaboration with the Japanese Society for Anesthesiologists. The present guidelines comprise 14 statements, five of which were judged to be valid on the highest evidence level and three on the second highest level. The guidelines are not intended to strongly recommend the use of sedation for gastrointestinal endoscopy, but rather to indicate the policy as to the choice of appropriate procedures when such sedation is deemed necessary. In clinical practice, the final decision as to the use of sedation should be made by physicians considering patient willingness and physical condition.

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“…Several oral and parenteral drugs are available (13) and widely used for sedating children for gastrointestinal endoscopy (14–16), but none fulfill all the criteria. Among the IV agents, propofol appears to be the most suitable for pediatric endoscopy and other invasive procedures (12,17–24) because of its shorter induction and recovery times and consistent achievement of deep sedation. The main barrier to its more widespread use by pediatric endoscopists has been its classification as an anesthetic agent, which limits its administration in most institutions to anesthesiologists and intensivists, thereby increasing the staffing needs and costs of the procedure.…”

Section: Discussionmentioning

confidence: 99%

Deep Sedation With Inhaled Sevoflurane for Pediatric Outpatient Gastrointestinal Endoscopy

Montes,

Bohn

2000

J. pediatr. gastroenterol. nutr.

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Background:Sevoflurane is an inhaled anesthetic agent with ideal properties for achieving deep sedation during pediatric outpatient gastrointestinal endoscopy. This is a comparison of experience with this gas and other sedation methods used in the authors' hospital.Methods:Retrospective chart review and statistical analysis of data from children receiving inhaled sevoflurane administered by an anesthesiologist through laryngeal insufflation, intravenous propofol, or intravenous midazolam‐fentanyl‐ketamine in any combination to achieve deep sedation for outpatient gastrointestinal endoscopy. Anesthesia was administered in a dedicated procedure room. The intravenous drugs were administered by pediatric intensivists in the intensive care unit. The same endoscopist performed all the procedures.Results:A total of 248 procedures were reviewed (midazolam‐fentanyl‐ketamine 67, propofol 114, and sevoflurane 67). All patients were adequately sedated with sevoflurane, and no intravenous access was required. Time (in minutes) to awakening (midazolam‐fentanyl‐ketamine 47.15, propofol 36.12, sevoflurane 5.70), discharge (midazolam‐fentanyl‐ketamine 141.99, propofol 91.20, sevoflurane 53.34), and total time, including induction and procedure (midazolam‐fentanyl‐ketamine 163.97, propofol 119.40, sevoflurane 73.93), were significantly lower for sevoflurane (P < 0.01). The complication rate for sevoflurane (4.5%) was lower (P < 0.05) than for midazolam‐fentanyl‐ketamine (13.4%) and for propofol (17.5%). Charges for room use and medications were also lower for sevoflurane (P < 0.01). The total charges for sedation (U.S.$) were comparable for sevoflurane (688.10) and propofol (723.08) but were higher for midazolam‐fentanyl‐ketamine (855.10, P < 0.01).Conclusions:Deep sedation with inhaled sevoflurane for pediatric outpatient gastrointestinal endoscopy is as safe as conventional sedation techniques, potentially less expensive, increases endoscopy unit productivity, and eliminates the inconvenience associated with obtaining intravenous access in children.

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Utilisation du Diprivan® pour les endoscopies digestives

Cited by 6 publications

References 27 publications

Safety and efficacy of target-controlled infusion versus intermittent bolus administration of propofol for sedation in colonoscopy: a randomized controlled trial

Safety and efficacy of target-controlled infusion versus intermittent bolus administration of propofol for sedation in colonoscopy: a randomized controlled trial

Guidelines for sedation in gastroenterological endoscopy

Deep Sedation With Inhaled Sevoflurane for Pediatric Outpatient Gastrointestinal Endoscopy

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