Utilidad de la siascopia en el diagnóstico de lesiones melanocíticas

Vea, Alvar; Barrera, Josefa; Velasco, Ana María Rivas; Casanova, Josep Manel; Matías‐Guiu, Xavier; Martí, Rosa M.

doi:10.1016/j.piel.2014.05.003

Cited by 1 publication

(2 citation statements)

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“…Patients with atypical naevus syndrome under digital follow‐up every 6–12 months with a SIAscopy (Spectrophotometric Intracutaneous Analysis, detailed information at supplementary material) system at the Dermatology Department of Arnau de Vilanova Hospital (Lleida, Catalonia, Spain) from April 2007 to July 2014 were registered. Employed SIAscopy programs were MoleManager ® for body mapping and MoleView ® for SIAscopic study of single lesions (Dermetics™) . Melanocytic lesions with the highest atypia of each patient (evaluated clinically and with the help of a hand‐held dermoscope) were recorded at baseline.…”

Section: Methodsmentioning

confidence: 99%

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Descriptive study of naevus involution in a series of 74 patients with atypical naevus syndrome under SIAscopy digital follow‐up

Moreno

Maiques

Gatius

et al. 2020

Acad Dermatol Venereol

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Background Characterization of nevi involution could help to understand the biological behaviour of melanocytic neoplasms. Objective To describe the frequency and morphology of naevus involution in a series of patients with atypical naevus syndrome under digital follow-up with a SIAscopy program and, in a small sample of fading nevi, to analyse histopathological features and immunohistochemical biomarkers. Methods Seventy-four patients registered from April 2007 to July 2014 in the SIAscopy system of the Department of Dermatology of Hospital Arnau de Vilanova of Lleida, Spain, were reviewed. Fourteen naevus cases with fading features were prospectively excised during follow-up. Eleven already excised naevus controls were randomly selected from our archive. Results We observed that 81% of patients showed, at least, one involutive naevus and 25% of recorded nevi presented this phenomenon; the mean time of involution was 46.7 months. The predominant structural pattern was reticular (>70%), and the most frequently observed regression structures were vascular (33.8%). Histopathological significant higher intensity of inflammatory infiltrate in controls and higher presence of laminar and compact fibrosis and increase of vessels in cases were demonstrated. Regarding immunohistochemical biomarkers, only higher expression of cytoplasmic activated caspase 3 in controls was significant. Conclusions Naevus involution is a common phenomenon in patients with dysplastic naevus syndrome. It is usually a slow process, more frequent in naevus with reticular pattern. SIAscopy regression structures are uncommon, with the exception of vascular ones. Histologically, fading involutive pattern is characterized by scarce inflammatory infiltrate and melanophages, delicate fibrosis and increase of vessels.

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Section: Methodsmentioning

confidence: 99%

“…SIAscopic characteristics of involutive nevi were recorded from colour, melanin and dermal melanin SIAgraphs as follows: structural pattern, type and percentage of depigmentation, involutive features, changes of global and dermal melanin ().…”

Section: Methodsmentioning

confidence: 99%