Utilidad de la 18 F-FDG PET/TC en el linfoma cerebral primario

de-Bonilla-Damiá, Á.; Fernández-López, Rosa; Capote-Huelva, F.J.; Cruz-Vicente, Fátima de la; Egea-Guerrero, Juan José; Borrego-Dorado, I.

doi:10.1016/j.remn.2017.03.006

Cited by 3 publications

(2 citation statements)

References 19 publications

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“…Primary CNS lymphoma lesions typically showed high uptake on PET with SUV max ranging from 5–39. However, some lesions visualized on MRI had no correlate on FDG PET ( 31 , 107 , 110 – 112 ) due to, e.g., small lesion size (usually <1 cm) and their pattern on MRI, such as disseminated presentation. Furthermore, leptomeningeal disease and eye involvement, diagnosed on CSF flow cytometry and vitreous aspirate, are usually not detectable on PET ( 31 ), due to small volume of FDG-avid disease or prominent FDG uptake in adjacent physiologic structures.…”

Section: Pet Imagingmentioning

confidence: 99%

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Positron emission tomography and magnetic resonance imaging in primary central nervous system lymphoma—a narrative review

et al. 2021

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This review addresses the challenges of primary central nervous system (CNS) lymphoma diagnosis, assessment of treatment response, and detection of recurrence. Primary CNS lymphoma is a rare form of extra-nodal non-Hodgkin lymphoma that can involve brain, spinal cord, leptomeninges, and eyes. Primary CNS lymphoma lesions are most commonly confined to the white matter or deep cerebral structures such as basal ganglia and deep periventricular regions. Contrast-enhanced magnetic resonance imaging (MRI) is the standard diagnostic modality employed by neuro-oncologists. MRI often shows common morphological features such as a single or multiple uniformly well-enhancing lesions without necrosis but with moderate surrounding edema. Other brain tumors or inflammatory processes can show similar radiological patterns, making differential diagnosis difficult. [18F]-fluorodeoxyglucose (FDG) positron emission tomography (PET) has selected utility in cerebral lymphoma, especially in diagnosis. Primary CNS lymphoma can sometimes present with atypical findings on MRI and FDG PET, such as disseminated disease, non-enhancing or ring-like enhancing lesions. The complementary strengths of PET and MRI have led to the development of combined PET-MR systems, which in some cases may improve lesion characterization and detection. By highlighting active developments in this field, including advanced MRI sequences, novel radiotracers, and potential imaging biomarkers, we aim to spur interest in sophisticated imaging approaches.

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Section: Pet Imagingmentioning

confidence: 99%

“…Few studies have investigated the utility of FDG PET/CT for monitoring response, mostly for MTX-based treatments, and detection of recurrence ( 88 , 110 , 111 , 113 , 123 ).…”

Section: Pet Imagingmentioning

confidence: 99%

Positron emission tomography and magnetic resonance imaging in primary central nervous system lymphoma—a narrative review

et al. 2021

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Intelligent Diagnosis and Analysis of Brain Lymphoma Based on DSC Imaging Features

Mao

Jiang

Zhao³

2022

Computational Intelligence and Neuroscience

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Currently, DSC has been extensively studied in the diagnosis, differential diagnosis, and prognosis evaluation of brain lymphoma, but it has not obtained a uniform standard. By combining DSC imaging features, this study investigated the imaging features and diagnostic value of several types of tumors such as primary brain lymphoma. At the same time, this study obtained data from brain lymphoma patients by data collection and set up different groups to conduct experimental studies to explore the correlation between IVIMMRI perfusion parameters and DSC perfusion parameters in brain lymphoma. Through experimental research, it can be seen that the combination of two perfusion imaging techniques can more fully reflect the blood flow properties of the lesion, which is beneficial to determine the nature of the lesion.

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Utility of flouro-deoxy-glucose positron emission tomography/computed tomography in the diagnostic and staging evaluation of patients with primary CNS lymphoma

Gupta

Purandare

et al. 2019

CNS Oncol.

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Aim: To prospectively assess the clinical utility of pretreatment flouro-deoxy-glucose positron emission tomography/computed tomography (18F-FDG-PET/CT) in patients with primary central nervous system (CNS) lymphoma (PCNSL). Materials & methods: Patients with suspected/proven PCNSL underwent baseline whole-body 18F-FDG-PET/CT. Maximum standardized uptake value and tumor/normal tissue ratios were compared between CNS lymphoma and other histological diagnoses. Results: The mean maximum standardized uptake value (27.5 vs 18.2; p = 0.001) and mean tumor/normal tissue ratio (2.34 vs 1.53; p < 0.001) of CNS lymphoma was significantly higher than other histologic diagnoses. Five of 50 (10%) patients with biopsy-proven CNS lymphomas had pathologically increased FDG-uptake at extraneuraxial sites uncovering systemic lymphoma. Conclusion: Pretreatment whole-body 18F-FDG-PET/CT provides valuable complementary information in the diagnostic and staging evaluation of patients with PCNSL to guide therapeutic decision-making.

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Utilidad de la 18 F-FDG PET/TC en el linfoma cerebral primario

Cited by 3 publications

References 19 publications

Positron emission tomography and magnetic resonance imaging in primary central nervous system lymphoma—a narrative review

Positron emission tomography and magnetic resonance imaging in primary central nervous system lymphoma—a narrative review

Intelligent Diagnosis and Analysis of Brain Lymphoma Based on DSC Imaging Features

Utility of flouro-deoxy-glucose positron emission tomography/computed tomography in the diagnostic and staging evaluation of patients with primary CNS lymphoma

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