Uteroglobin-like antigen in the pulmonary epithelium and secretion of the lung

Abstract

The immunological identity of a uteroglobin-like protein, occurring in respiratory tract secretions and tissue, with uteroglobin from rabbit endometrial secretion is demonstrated. A uteroglobin-like antigen has been localized in bronchial epithelial cells and in bronchioles by immunofluorescence. This secretory protein is, in contrast to the authentic uteroglobin, hormone-independent, as far as estrogens and progesterone are concerned. The possible significance of comparative studies on uteroglobin and the uteroglobin-like antigen is discussed, taking into account cytological, endocrinological, and molecularbiological aspects.

Uteroglobin/Clara Cell 10‐kDa Family of Proteins: Nomenclature Committee Report

“…Later, it turned out that the same protein is also expressed in other tissues in significant amounts. Soon after the discovery of uteroglobin, for example, a uteroglobin‐like antigen or protein 1 was detected in the rabbit lung 2 and male genital tract. 3 By comparing numerous biochemical and physicochemical parameters, purified uteroglobin‐like protein from rabbit lung and uteroglobin from the uterus were shown to be identical.…”

Regulation of CCSP (PCB-BP/Uteroglobin) Expression in Primary Cultures of Lung Cells: Involvement of C/EBP

“…In lung, CCSP is specifically extions in the respiratory system (Gail and Lenfant, 1983). The pressed in the bronchiolar Clara cells, as well as in similar cells bronchiolar epithelium is located in the transition between the in the bronchi and trachea (Lund et al, 1988a; Singh et al, functionally distinct conducting and respiratory portions of the 1988b; Beier et al, 1978). The expression is under hormonal airways.…”

Uteroferrin : a mechanism of maternal to fetal iron transport in swine / by Charles Andrew Ducsay.

“…Uteroglobin comprises the major protein fraction from rabbit uterine flushings from the period after ovulation until implantation (Beier, 1968(Beier, , 1973 Of interest is the fact that a uteroglobin-like protein has been identified in rabbit bronchial secretions as well as in seminal plasma Noske and Feigelson, 1976;Beier et al , 1978).…”