Uterine Sarcoma: A Report of 10 Cases Studied by Transvaginal Color and Pulsed Doppler Sonography

Kurjak, Asım; Kupešić, Sanja; Shalan, Hesham; Jukić, Silvana; Kośuta, D; Ilijaš, Marijan

doi:10.1006/gyno.1995.9965

Cited by 62 publications

(36 citation statements)

References 4 publications

(7 reference statements)

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“…Kurjak et al 4 reported that RI values below a cutoff point of 0.4 had a sensitivity of 90.9% and a specificity of 99.8% in the diagnosis of sarcomas without differentiating between sarcoma subtypes. However, Hata et al 5 found no difference in RI values between 5 patients with uterine sarcoma and 41 patients with LM, perhaps because the sarcoma group included 4 LMS and only 1 MMMT.…”

Section: Discussionmentioning

confidence: 98%

Uterine sarcomas versus leiomyomas: Gray‐scale and Doppler sonographic findings

Aviram

Ochshorn

Markovitch

et al. 2004

J of Clinical Ultrasound

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Section: Discussionmentioning

confidence: 98%

Uterine sarcomas versus leiomyomas: Gray‐scale and Doppler sonographic findings

Aviram

Ochshorn

Markovitch

et al. 2004

J of Clinical Ultrasound

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“…However, there are no specific criteria to differentiate leiomyosarcoma from benign leiomyoma prior to surgery. Although considered as not biological related, there are numerous studies which tried to differentiate a LM from a LMS on imaging, using MRI, PET or ultrasound examinations which provide no specific characteristics for a malignant tumor [10][11][12][13][14], and CT exam limited mainly for the evaluation of extrauterine metastases [10,15]. These data confirm once more that the decisive and accurate diagnosis is made by histological evaluation, other methods providing only suggestive features [10].…”

Section: Discussionmentioning

confidence: 81%

Diagnosis challenges in a uterine leiomyosarcoma

Balan¹,

Andriescu²,

Marin³

et al. 2017

Arch Clin Cases

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Uterine leiomyosarcoma (LMS) represents a rare tumor, accounting for 1.3% of all uterine malignancies. Although this tumor shares morphological and clinical features with other uterine benign and malignant tumors, the accurate diagnosis is necessary, due to their different biological behavior and prognosis. Therefore, we present a case of LMS in a 48 year-old patient, complaining of a 3-months metrorrhagia. The tumor presented as a poorly defined submucosal nodule, with a soft consistence and measuring 6 cm in diameter. The microscopic examination of this tumor nodule revealed fascicles of spindle cells, with pleomorphic hyperchromatic nuclei exhibiting moderate to severe atypia and areas of tumor necrosis. At least 5 atypical mitoses/ 10 HPF were also found. Immunohistochemistry technique, with a panel of six antibodies, comprising ER, PR, PCNA, SMA, p53, and bcl-2, has been performed for the differential diagnosis. The final histopathological diagnosis was that of uterine LMS. Considering LMS an aggressive tumor, the patient has been recommended a thorough follow-up.

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“…There is a low propensity for pelvic node involvement, but CT has been the most common imaging modality for investigating the presence and extent of extra-uterine disease and distant metastasis [27]. Imaging by ultrasound may reveal increased vascularity indicative of malignancy [28]. Further investigation is required for FDG-PET to be established as an imaging modality for leiomyosarcomas [29].…”

Section: Discussionmentioning

confidence: 99%

Uterine Leiomyosarcoma Manifesting as a Tricuspid Valve Mass

et al. 2013

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Uterine leiomyosarcoma is a rare malignancy and carries a poorer prognosis when compared to endometrial carcinoma. It has been observed to metastasize to all the major organs. It presents with symptoms of abdominal distension, vaginal bleeding and may pass unnoticed until an advanced stage in patients with leiomyomas. Surgery is a viable option in patients with disease limited to the uterus, but metastasis to the heart may require surgery to prevent acute and catastrophic complications. The case described here involves metastasis to the tricuspid valve, which caused severe tricuspid regurgitation in the setting of acute pulmonary embolism. Surgical resection restored cardiac function and stabilized the patient. This case illustrates a rare site of metastasis of leiomyosarcoma which required immediate intervention and resulted in a favorable outcome.

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Uterine Sarcoma: A Report of 10 Cases Studied by Transvaginal Color and Pulsed Doppler Sonography

Cited by 62 publications

References 4 publications

Uterine sarcomas versus leiomyomas: Gray‐scale and Doppler sonographic findings

Uterine sarcomas versus leiomyomas: Gray‐scale and Doppler sonographic findings

Diagnosis challenges in a uterine leiomyosarcoma

Uterine Leiomyosarcoma Manifesting as a Tricuspid Valve Mass

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