Uterine Intravenous Leiomyomatosis with Intracardiac Extension and Pulmonary Benign Metastases on FDG PET/CT: A Case Report

Wang, Hui‐Chun; Wang, Yu Bin; Chen, Xiao Hong; Cui, Lan Lan

doi:10.3348/kjr.2016.17.2.289

Cited by 10 publications

(7 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It was first described by Birch-Hirschfeld in 1896 [3] while IVL with the cardiac extension was first reported in 1907 by Dürck [2,4]. An extrauterine leiomyoma occurs in 30% of cases and IVL with the cardiac extension has been reported in approximately 10% of cases [1]. In 2015, Fornaris et al [2] reported a case of IVL with extension to the pulmonary artery.…”

Section: Discussionmentioning

confidence: 99%

“…An IVL is a rare [1] and potentially life-threatening tumor [2]. It was first described by Birch-Hirschfeld in 1896 [3] while IVL with the cardiac extension was first reported in 1907 by Dürck [2,4].…”

Section: Discussionmentioning

confidence: 99%

“…Intravenous leiomyomatosis (IVL) is a benign smooth muscle cell tumor of uterine origin. The tumor can extend through the pelvic veins, renal veins and inferior vena cava (IVC) into the right atrium (RA) or as far as the pulmonary artery [1]. IVL can cause dyspnea, chest pain, heart failure and sudden death [2,3].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Intravenous Leiomyomatosis Extending from the Uterus to the Heart

Yusof

Ramli

Yahaya

et al. 2019

Cardiovasc Imaging Asia

View full text Add to dashboard Cite

We report a case of intravenous leiomyomatosis with right atrium extension through the left gonadal vein, left renal vein and inferior vena cava. The tumor moved in and out of the right ventricle via the tricuspid valve, which could lead to valve obstruction and sudden death. We illustrate the importance of multimodality cardiac imaging to diagnose this condition by performing echocardiography, cardiac magnetic resonance imaging and computed tomography.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Intravenous Leiomyomatosis Extending from the Uterus to the Heart

Yusof

Ramli

Yahaya

et al. 2019

Cardiovasc Imaging Asia

View full text Add to dashboard Cite

show abstract

“…Although all three entities are rare, intravenous extension into the heart is the most common, with more than 100 reported cases since the early 1900s [2], and the least reported type is benign metastasizing leiomyoma It is not excluded, without being proven, that their physiopathology is common [14,15]. Furthermore, it is necessary to confirm the diagnosis by histological examination in order to rule out the differential diagnosis of leiomyosarcoma, which may have the same clinical characteristics as benign metastatic leiomyoma [16][17]. To the best of our knowledge, there are only four prior case reports of benign metastasizing leiomyoma to the heart (Table 1) [1,3,4].…”

Section: Discussionmentioning

confidence: 99%

Benign Metastatic Leiomyoma: Unusual Heart Location

Elaouni¹,

Jebli²,

Sassi³

et al. 2021

austinjpathollabmed

View full text Add to dashboard Cite

Cardiac smooth muscle tumors are rare; three different clinical settings for these tumors have been reported, including benign metastasizing leiomyoma from the uterus, primary cardiac leiomyoma and leiomyosarcoma, and intravenous cardiac extension of pelvic leiomyoma, which is the most common. We present a case of a 56-year-old woman with a benign metastasizing leiomyoma to the heart without associated pulmonary localization 15 years after endoscopic vaginal myomectomy of polymyomatous uterus. Immunohistochemical stains for H-Caldesmon, Desmin, and estrogen, progesterone receptors were positive, indicating a smooth muscle tumor of uterine origin. To our knowledge, this is only the fifth reported case of benign metastasizing leiomyoma to the heart with histological proof and the first case of earlier onset cardiac metastasis without pulmonary metastasis localization. It illustrates that benign metastasizing leiomyoma should be included in the differential diagnosis of cardiac tumors in patients with a history of surgery uterine leiomyoma perfectly benign.

show abstract

“…Although IVL is histologically benign, the tumor has the potential to be clinically aggressive due to its massive intraluminal growth. In most cases, IVL is limited to the pelvic veins, and in rare instances, may extend through the inferior vena cava (IVC) to the right heart chambers (causing intracardiac leiomyomatosis (ICL) (2). Further intracardiac spread into the main pulmonary artery is potentially life-threatening.…”

Section: Introductionmentioning

confidence: 99%

Cardiovascular Ultrasonographic Features and Clinical Findings for Intravenous Leiomyomatosis: A Case Report

Wang³

2017

Iran Red Crescent Med J

View full text Add to dashboard Cite

Introduction: To summarize the vascular ultrasonographic features of intravenous leiomyomatosis (IVL) and assess the role of this method for the accurate diagnosis of patients with IVL. The current study was carried out in Shandong provincial hospital affiliated to Shandong university and Shandong medical imaging research institute, Shandong university of Jinan, Shandong province, P.R. China in 2017. Case Presentation: The 9 samples of IVL were collected from patients undergone surgery from July 2007 to December 2016 in the department of gynecology of the hospital. The clinical data, vascular ultrasonographic findings, and histologic results were retrospectively reviewed. Six patients underwent computed tomography (CT) and 3 patients were examined by magnetic resonance imaging (MRI). Clinical symptoms included lower extremity edema, chest congestion, and syncope. Any pelvic masses found were identified. On ultrasonography, the internal iliac vein, common iliac vein, and the inferior vena cava (IVC) were all involved with dilated veins and isoechoic masses noted in all 9 patients. The right ovarian vein was involved in 2 patients, and in 3 patients, masses had emerged in the IVC and spread into the right atrium, at times intruding into the tricuspid orifice during diastole. All 9 patients underwent a 1-stage thoracoabdominal surgical procedure. There was no documented recurrence of the masses in 7 patients and in the remaining 2 patients; solid pelvic masses were detected 3 or 6 months after the surgery. No intravascular masses were detected. Conclusions: Ultrasonography is performed to evaluate the features and path of extension of IVL. Patients diagnosed with uterine leiomyoma or hysterectomy were at greater risk of developing IVL. Vascular ultrasound could be used as an additional diagnostic tool for IVL screening and diagnosis in patients at an early age.

show abstract

Uterine Intravenous Leiomyomatosis with Intracardiac Extension and Pulmonary Benign Metastases on FDG PET/CT: A Case Report

Cited by 10 publications

References 8 publications

Intravenous Leiomyomatosis Extending from the Uterus to the Heart

Intravenous Leiomyomatosis Extending from the Uterus to the Heart

Benign Metastatic Leiomyoma: Unusual Heart Location

Cardiovascular Ultrasonographic Features and Clinical Findings for Intravenous Leiomyomatosis: A Case Report

Contact Info

Product

Resources

About