Uterine didelphys with concomitant renal anomalies in both mother and fetus

Boehnke, Maren; Zaretsky, Michael V.; Soranno, Danielle E.; Dannull, Kimberly; Tucker, Bethany; Marwan, Ahmed I.

doi:10.1016/j.epsc.2016.08.008

Cited by 5 publications

(8 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The appropriate development, fusion and resorption of this wall is thought to be induced by the Wolffian ducts located at both sides (which, in combination with the Müllerian tubercle give rise to the vagina). The absence or distal injury of one of the Wolffian ducts may give rise to renal agenesis, ipsilateral blind or atretic hemivagina and uterine anomalies (fusion or resorption defect) 1 2. When the ureteric bud arises more cephalad than normal on the mesonephric duct, distal ectopic ureteric insertion may occur as it migrates more caudally before inserting into either the distal urinary tract or reproductive tract 3–5.…”

Section: Discussionmentioning

confidence: 99%

“…Interestingly, it has been suggested in the literature that uterine didelphys with renal abnormalities tends to affect the right side more often than the left 1 8. Vercellini et al performed a meta-analysis of 36 such reports and supported a true predominance 9…”

Section: Discussionmentioning

confidence: 99%

“…In this scenario, patients only become symptomatic with incontinence after vaginoplasty (vaginal septum excision) had been performed. Renal abnormalities have been seen in 15%–30% of non-obstructed uterine didelphys 1…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Novel approach to locating a hypoplastic kidney in a unique variant of uterine didelphys syndrome presenting with continuous incontinence

2019

View full text Add to dashboard Cite

Mullerian abnormalities such as uterine didelphys have an association with renal abnormalities. Ureteric ectopia must be considered as a differential diagnosis of incontinence. We describe the case of a 21-year-old woman who presented with low volume continuous incontinence with a history of right renal agenesis and uterus didelphys. A right kidney was not identified on CT intravenous pyelogram but excretory phase images suggested the presence of a right ureter. Diethylenetriaminepentaacetic acid renogram confirmed an area of perfusion consistent with a poorly functioning right kidney remnant. Cystoscopic investigation demonstrated an orthotopic left ureteric orifice, and an ectopic right ureteric orifice was identified in the posterior fornix of the right vagina. A laparoscopic right nephrectomy was performed, with a new application of indocyanine green aiding in identification of the right hypoplastic kidney with fluorescence imaging. The patient recovered well postoperatively and experienced complete resolution of incontinence, with preserved normal renal function.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Novel approach to locating a hypoplastic kidney in a unique variant of uterine didelphys syndrome presenting with continuous incontinence

2019

View full text Add to dashboard Cite

show abstract

“…Because of the close association and developmental interrelation between the 2 tracts, Mullerian duct abnormalities are usually related to Wolffian duct abnormalities which cause congenital anomalies in the kidneys and urinary tracts. 2 Cervical agenesis is classified as a type of Mullerian IB anomaly, according to the American Society of Fertility, is the result of an abnormal fusion of the Mullerian channel with urogenital sinus, or segment atrophy that normally forms the Mullerian system. The incidence of cervical agenesis is 0.01% in the general population.…”

Section: Introductionmentioning

confidence: 99%

Uterus Didelphys dengan Agenesis Servik Bilateral

Rizary¹,

Hendry²

2020

AOJ

View full text Add to dashboard Cite

Background : The mullerian duct anomaly is a congenital abnormality of the female reproductive system caused by abnormal embryological development during pregnancy. If accompanied by cervical agenesis and infertility, intervention must be taken. Accurate diagnosis and proper treatment are very crucial to the future of reproduction and treatment of infertility in patients. Objective: Reporting the handling of cases of uterine didelphys accompanied by bilateral cervical agenesis. Method : Case report Case: Reported cases of women aged 34 years with primary amenorrhea and 9 years primary infertility, not typical cyclic pain, normal secondary sex development and from gynecological examination obtained cervical agenesis. Transvaginal ultrasound examination found a mass with the appearance of adenomyosis. Laparoscopic performed show 2 masses, 1 mass resembling adenomyosis with a size of 9x6x5cm located lateral to the left pelvis and another mass in the form of a hypoplastic uterus with a size of 2x2x1cm visible 2 tubes with 2 ovaries within normal limits. Uterine mass resembling adenomyosis with a location far from the vagina making it difficult to do anastomoses while other uterus hypoplasia and non-functional. Hysterectomies were performed on the mass of adenomyosis with the results of PA was adenomyosis. Conclusion: The uterus didelphys with bilateral cervical agenesis with 1 uterine adenomyosis and located in the pelvic lateral it was difficult to do uterovaginal anastomose so that hysterectomy was performed. Second uterine was hypoplasia and non-functional so that no action was taken. Need to think about "future fertility" in these patients and various options for having children.

show abstract

“…1 About 15-30% of non-obstructed uterine didelphys may be associated with renal anomalies of which renal agenesis is the most frequent. 2 The female reproductive system develops from the paired mullerian ducts. Mullerian ducts develop lateral to Wolffian ducts at around 6-8 weeks' gestation and then migrate medially to fuse in the midline at around 10th week of gestation to form the uterovaginal canal after incorporating with the urogenital sinus.…”

Section: Introductionmentioning

confidence: 99%

Failure of intrauterine contraception in a multigravida lady with an undiagnosed uterus didelphys: a case report

Bhattacharyya

Sarkar²

2020

Int J Reprod Contracept Obstet Gynecol

View full text Add to dashboard Cite

Uterus didelphys remains one of the rarest uterine anomalies partly because; majority women experience no symptoms with an uneventful reproductive life. Despite the cost-effectiveness and efficacy paired with fewer side effects and convenience of using an intrauterine contraceptive device, it is most likely to prove futile in an unsuspected case of didelphic uterus resulting in an unintended pregnancy. Hence, intrauterine contraception is generally considered a contraindication in cases of uterine malformations. We present a case of a multigravida mother (G7 P3 L3 A3) with a history of three term vaginal deliveries, with an undiagnosed uterus didelphys, carrying a single live intrauterine pregnancy of approximately 6 weeks period of gestation, in the right uterine horn and a copper containing intrauterine contraceptive device in the left uterine horn, willing to undergo medical termination of pregnancy. A high index of suspicion, on the part of the gynaecologist as well as the radiologist, is required to investigate concurrent pregnancy with a history of an intrauterine contraceptive device insertion, in order to rule out rarer uterine malformations like uterus didelphys. Thorough history taking and clinical examination accompanied by improved imaging techniques should be performed at the time of first pregnancy in order to avoid an unsuitable placement of an intrauterine contraceptive device.

show abstract

Uterine didelphys with concomitant renal anomalies in both mother and fetus

Cited by 5 publications

References 10 publications

Novel approach to locating a hypoplastic kidney in a unique variant of uterine didelphys syndrome presenting with continuous incontinence

Novel approach to locating a hypoplastic kidney in a unique variant of uterine didelphys syndrome presenting with continuous incontinence

Uterus Didelphys dengan Agenesis Servik Bilateral

Failure of intrauterine contraception in a multigravida lady with an undiagnosed uterus didelphys: a case report

Contact Info

Product

Resources

About