Usual and Advanced Monitoring in Patients Receiving Oxygen Therapy

Lellouche, François; L’Her, Erwan

doi:10.4187/respcare.07623

Cited by 7 publications

(3 citation statements)

References 92 publications

(103 reference statements)

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“…This technique comes with a way to measure its success. The majority of doctors employ noninvasive monitoring methods like pulse oximetry, arterial blood gases, or partial pressure of oxygen (PaO2) to help in their clinical assessment (34) .…”

Section: Monitoring Of Oxygen Therapymentioning

confidence: 99%

Oxygen Therapy and Their Risk in The Premature Neonates: Review Article

Eltaky¹

2022

The Egyptian Journal of Hospital Medicine

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Background: Neonatal respiratory care includes oxygen therapy, which is more common due to the improved survival rates of premature infants. Considering that most current studies demonstrate that preterm newborns benefit most from oxygen saturations (SpO2) of 91-95 percent, which reduces the risk of complications such as retinopathy of prematurity, we set out to study oxygen treatment and its risks in premature neonates. Objective: The reviews article highlight oxygen therapy and their risk in the premature neonates. Conclusion:There have been improvements in outcomes for babies with extremely low birth weight when using a larger goal range (85%-93%), but these ranges have not been thoroughly assessed in major clinical trials; additional data is required. High oxygen levels may be avoided with early use of a pulmonary vasodilator.

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Section: Monitoring Of Oxygen Therapymentioning

confidence: 99%

Oxygen Therapy and Their Risk in The Premature Neonates: Review Article

Eltaky¹

2022

The Egyptian Journal of Hospital Medicine

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“…Pulse oximetry estimates PaO 2 indirectly by calculating the rate of light absorption at different wavelengths. PaO 2 between 60 and 100 mmHg shows a linear correlation with peripheral hemoglobin oxygen saturation (SpO 2 ); for this reason, this monitoring is a noninvasive, rapid, and easy method to guide oxygen therapy [7,8]. During hyperoxaemia, for PaO 2 > 100 mmHg, the pulse oximeter displays a SpO 2 > 98%, limiting its clinical relevance because it does not provide information on an impending decrease in PaO 2 or whether the oxygen flow rate is causing severe hyperoxaemia with possible secondary atelectasis [9].…”

Section: Introductionmentioning

confidence: 99%

Oxygen Reserve Index as a Tool to Monitor Four Techniques of Oxygen Supplementation at Different Flow Rates in Dogs Sedated with Dexmedetomidine and an Opioid

Bellini,

De Benedictis

2023

Animals

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Respiratory dysfunction often decreases arterial oxygen content. Four common oxygen delivery techniques—flow-by, nasal prongs, a tight-vented mask, and a tight mask connected to a Venturi valve—were evaluated for their effectiveness in increasing the oxygen reserve index (ORi), a dimensionless index of oxygen content that provides additional information compared to traditional pulse oximetry (SpO2) during hyperoxia (PaO2 100–200 mmHg), and that ranges from 0 to 1. Thirty-two dogs sedated with dexmedetomidine and an opioid were evenly divided into four groups based on the technique for oxygen administration. Each dog received oxygen at 1, 2, and 3 L/min by a single technique, and the amount of inhaled oxygen (FiO2) was measured at the level of the cervical trachea. At each flow rate, ORi and SpO2 were recorded. The flow-by method minimally increased the FiO2, and ORi reached its highest value only in 3 out of 8 dogs at the maximum flow rate. Other methods exhibited direct correlations between the oxygen flow rate and ORi (p < 0.001). These methods effectively increased FiO2 and ORi, with over half of the values exceeding 40% and 0.4, respectively. The tight-vented mask showed variable increases in FiO2, ranging between 22 and 90%. Despite method-dependent variations, all devices increased SpO2 > 98% as the FiO2 increased (p = 0.002). In conclusion, nasal prongs and the mask connected to the Venturi valve showed the highest correlation between the oxygen flow rate and the ORi. These results suggest that using these two techniques in conjunction with ORI can help in optimizing oxygen therapy.

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“…Restoring spontaneous circulation and preventing hypoxic ischemic tissue injury are the goals of CPR ( 13 ). As sufficient oxygen delivery is required to restore and maintain the energy state of the heart, the use of maximal inspired oxygen (O 2 ) concentrations during CPR and of earlier post-resuscitation are recommended in the European Resuscitation Council Guidelines 2021( 14 ).…”

Section: Introductionmentioning

confidence: 99%

Hydrogen therapy after resuscitation improves myocardial injury involving inhibition of autophagy in an asphyxial rat model of cardiac arrest

et al. 2022

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Hydrogen (H 2 ) therapy is a therapeutic strategy using molecular H 2 . Due to its ability to regulate cell homeostasis, H 2 therapy has exhibited marked therapeutic effects on a number of oxidative stress-associated diseases. The present study investigated the effectiveness of H 2 therapy in protecting against myocardial injury in a rat model of asphyxial cardiac arrest and cardiopulmonary resuscitation. Rats underwent 10-min asphyxia-induced cardiac arrest (CA) and cardiopulmonary resuscitation (CPR), and were randomly divided into control and H 2 therapy groups. After resuscitation, the H 2 therapy group was administered room air mixed with 2% H 2 gas for respiration. During CA/CPR, the arterial pressure and heart rate were measured every minute. Survival rate, cardiac function, myocardial injury biomarkers creatine kinase-MB and cardiac troponin-T, and histopathological changes were evaluated to determine the protective effects of H 2 therapy in CA/CPR. Immunohistochemistry and western blot analysis were used to determine the expression levels of autophagy-associated proteins. In vitro , H9C2 cells were subjected to hypoxia/reoxygenation and H 2 -rich medium was used in H 2 treatment groups. Western blotting and immunofluorescence were used to observe the expression levels of autophagy-associated proteins. Moreover, an adenovirus-monomeric red fluorescent protein-green fluorescent protein-LC3 construct was used to explore the dynamics of autophagy in the H9C2 cells. The results showed that H 2 therapy significantly improved post-resuscitation survival and cardiac function. H 2 therapy also improved mitochondrial mass and decreased autophagosome numbers in cardiomyocytes after resuscitation. The treatment inhibited autophagy activation, with lower expression levels of autophagy-associated proteins and decreased autophagosome formation in vivo and vitro . In conclusion, H 2 gas inhalation after return of spontaneous circulation improved cardiac function via the inhibition of autophagy.

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Usual and Advanced Monitoring in Patients Receiving Oxygen Therapy

Cited by 7 publications

References 92 publications

Oxygen Therapy and Their Risk in The Premature Neonates: Review Article

Oxygen Therapy and Their Risk in The Premature Neonates: Review Article

Oxygen Reserve Index as a Tool to Monitor Four Techniques of Oxygen Supplementation at Different Flow Rates in Dogs Sedated with Dexmedetomidine and an Opioid

Hydrogen therapy after resuscitation improves myocardial injury involving inhibition of autophagy in an asphyxial rat model of cardiac arrest

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