2005
DOI: 10.1590/s0004-27492005000400022
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Uso do fluconazol endovenoso no tratamento da endoftalmite fúngica endógena: relato de caso

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Cited by 6 publications
(5 citation statements)
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“…The authors report a case of bilateral endogenous fungal endophthalmitis following nephrolithiasis complicated by obstructive pyelonephritis in an adult female patient who had some risk factors for fungal infection known as: recent hospitalization, central venous access, and severe upper urinary tract infection (2) . Fungal endophthalmitis is usually an indolent bilateral infection in ¼ of cases, and the most common symptoms are visual blur and photophobia.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…The authors report a case of bilateral endogenous fungal endophthalmitis following nephrolithiasis complicated by obstructive pyelonephritis in an adult female patient who had some risk factors for fungal infection known as: recent hospitalization, central venous access, and severe upper urinary tract infection (2) . Fungal endophthalmitis is usually an indolent bilateral infection in ¼ of cases, and the most common symptoms are visual blur and photophobia.…”
Section: Discussionmentioning
confidence: 99%
“…In the last decades, the increase in incidence has been influenced by several factors, such as the diffusion of antibiotic therapy, intravenous catheterization, the use of prolonged parenteral nutrition, immunosuppression caused by systemic disease or induced immunosuppressive therapy, the use of illicit drugs and prematurity at birth (2) . Currently, amphotericin B is used as first-line treatment in fungal endophthalmitis, despite its local and systemic toxicity.…”
mentioning
confidence: 99%
“…Fluconazole has excellent penetration into the vitreous (35). A case of endogenous Candida albicans endophthalmitis in a newborn refractory to intravenous amphotericin B that responded to fluconazole has been reported (14). Itraconazole is active against a variety of fungi and is well absorbed orally in doses of 50 to 400 mg daily.…”
Section: Discussionmentioning
confidence: 99%
“…Systemically administered voriconazole which would be given simultaneously with intravitreal injection would penetrate into the vitreous. In addition to voriconazole, fluconazole also penetrates well into the vitreous, and both agents have been effective in treating fungal endophthalmitis through intravenous administration (14,15). Intravitreal injection of liposomal amphotericin B, which has less toxicity than amphotericin B, was used to treat a patient with bilateral endogenous Candida endophthalmitis (16).…”
mentioning
confidence: 99%
“…However, there are reports of successful treatment of endogenous endophthalmitis by Candida spp. with FCZ (89)(90)(91) . Even though its ocular penetration is superior to KCZ, in vitro and in vivo studies showed that the antifungal spectrum of FCZ is narrower.…”
Section: -Fluconazolementioning
confidence: 99%