Uso de las tecnologías de secuenciación masiva para el diagnóstico y epidemiología de enfermedades infecciosas

Approach to COVID-19 pandemic management in Madrid. Chronic of a year

“…However, the development of massive whole genome sequencing techniques, based on next-generation sequencing (NGS) methods, allows millions to billions of DNA copies to be sequenced in a single run [12]. Despite its bioinformatics requirements, this methodology is gradually being incorporated into genomic studies in clinical care and epidemiological surveillance at a cost and scale hitherto inaccessible [13]. For the time being, its main application has been the characterization of the successive phenotypically and genotypically different SARS-CoV-2 variants that have emerged in recent months.…”