Using β hCG, prolactin and IGFBP I single or in Pairs to diagnose PROM

Comparative study between the effect of home and hospital management on latent period of pre-labor rupture of membranes

“…Sterile speculum examinations deliver a chance to check for cervicitis and prolapses of the umbilical cord or fetal organs, evaluate cervical dilatations and effacement, and get cultures as proper. The diagnosing of membrane ruptures characteristically is established by conservative clinical assessment, which comprises the visualizations of amniotic fluids moving from the cervical channel and pooling in the vagina, a simple pH examination of vaginal fluids, or arborizations (ferning) of dried vaginal fluids, that is recognized under microscopic assessment 4 .The period from membranes ruptures and onset of labor is called the latent period. Some authorities advocate there must be a minimum latent period (such as 1 hour to 4 hours) for the diagnosis of PROM to stand.…”