Multiple stakeholders in literacy clinics around the world were affected by pivoting from face-to-face or online to totally remote platforms during the COVID-19 pandemic. This chapter, after providing some contextual descriptions and theoretical framing, explores findings from two literacy clinics in the United States, one in a rural Midwest area and the other in an urban region along the Eastern Seaboard. The implications from these two sites are representative of other literacy clinics across North America and elsewhere as they made necessary adaptations because of COVID-19.