Using the Nextflow framework for reproducible in-silico omics analyses across clusters and clouds

Abstract

Reproducibility has become one of biology’s most pressing issues. This impasse has been fuelled by the combined reliance on increasingly complex data analysis methods and the exponential growth of biological datasets. Nextflow is a pipeline orchestration tool that has been designed to ease deployment and guarantee reproducibility across platforms. It allows the seamless parallelization and deployment of any existing application with minimal development and maintenance overhead, irrespective of the original programming language. These capabilities guarantee consistent results over time and across different computing platforms.