Using the neutrophil-to-lymphocyte ratio to predict outcomes in pediatric patients with traumatic brain injury

Kimball, Rebekah; Shachar, Elad; Eyerly-Webb, Stephanie; Patel, Daxa; Spader, Heather S.

doi:10.1016/j.clineuro.2020.105772

Cited by 11 publications

(22 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Research by Masoum et al in Iran in 2018 showed the same results with an average GCS score at the time of admission was 8.6 ± 3.5, and at the end of the study was 12.9 ± 3.5 . 59,64,65 In this study the average leukocyte value was 84,85,86,87 In this study showed that the average lymphocyte levels based on the severity of mild…”

Section: Introductionmentioning

confidence: 53%

Comparison of Lymphocyte Neutrophil Ratio in Head Injury Patients with Blood and without Intracranial Bleeding in Dr. M. Djamil Hospital

Hafiz

Saanin

Ningsih

2021

BJI

View full text Add to dashboard Cite

A B S T R A C TBackground: Head injuries occur every 15 seconds worldwide, with patientsdying every 12 minutes. The value of the Neutrophil Lymphocyte Ratio (NLR) is afactor that influences the assessment and prognostic value of patients withintracranial hemorrhage and without intracranial hemorrhage in head injury.The aim of this study was to determine the relationship between increased NLRbased on the severity of head injury patients with or without intracranialhemorrhage. Methods: This study is a retrospective cross sectional study of headinjury patients with hemorrhage and without intracranial hemorrhage who weretreated at Dr. M. Djamil Hospital Padang in 2020 from May to December 2020.Data was collected in the Medical Records Department of Dr. M. Djamil HospitalPadang who met the inclusion and exclusion criteria. Results : A total of 92patients were included in the inclusion criteria for this study. The results showedthat the mean NLR value in head injury patients was 11.72 with a variation of7.31. The mean NLR level based on the severity of mild head injury was 10.15with a variation of 6.38. The mean NLR level of moderate head injury severity was12.70 with a variation of 7.09. The mean NLR level of severe head injury, was14.69 with a variation of 9.30. The results showed that there was no difference inthe mean of NLR levels in mild head injury patients with hemorrhage and withoutintracranial hemorrhage. The results showed that there was a significantrelationship between NLR levels in moderate head injury patients withhemorrhage (14.20) and without intracranial hemorrhage (7.20) (p value = 0.029),whereas in severe head injury it could not be assessed because there was nosample without hemorrhage. Conclusion: There is an association betweenincreased NLR and intracranial bleeding in moderate head injury patients

show abstract

Section: Introductionmentioning

confidence: 53%

Comparison of Lymphocyte Neutrophil Ratio in Head Injury Patients with Blood and without Intracranial Bleeding in Dr. M. Djamil Hospital

Hafiz

Saanin

Ningsih

2021

BJI

View full text Add to dashboard Cite

show abstract

“…A higher NLR value is an independent predictor of poorer functional outcome and a higher mortality rate in patients with head injury and correlates with a lower GCS score. 59,60 Based on the result of this research, there was no significant correlation between NLR levels in minor head injury patients with intracranial hemorrhage or without intracranial hemorrhage (p value = 0,930). The results showed that there was a correlation between an increase in NLR levels in moderate head injury patients with intracranial hemorrhage and without intracranial hemorrhage (p value = 0,029).…”

Section: Discussionmentioning

confidence: 77%

Comparison of Neutrophil Lymphocyte Ratio in Traumatic Head Injury Patients With and Without Intracranial Hemorrhage at Dr. M. Djamil Hospital

Hafiz¹,

Saanin²,

Ningsih³

2021

Indonesian Journal of Neurosurgery

View full text Add to dashboard Cite

Background: Head injuries occur evry 15 seconds worldwide, with patients dying every 12 minutes. The value of the Neutrophil Lymphocyte Ratio (NLR) is a factor that influences the assessment and prognostic value of patients with intracranial hemorrhage and without intracranial hemorrhage in head injury. Objective: The aim of this study was to determine the relationship between increased NLR based on severity of head injury patients with or without intracranial hemorrhage. Methods: This study is a retrospective cross sectional study of head injury patients with hemorrhage and without intracranial hemorrhage who were treated at Dr. M. Djamil Hospital Padang in 2020 from May to December 2020. Data was collected in the Medical Records Department of Dr. M. Djamil Hospital Padang who met the inclusion and exclusion criteria. Results: The results showed that there was a significant relationship between NLR levels in moderate head injury patients with hemorrhage (14,20) and without intracranial hemorrhage (7,20) (p value = 0.029), whereas in severe head injury it could not be assessed because there was no sample without hemorrhage. Conclusion:There is an association between increased NLR and intracranial bleeding in moderate head injury patients.

show abstract

“…Knowing the RNL value early can be an indicator for doctors for intensive care of head injury patients and predict outcomes. [24][25][26]…”

Section: Resultsmentioning

confidence: 99%

Neutrophil-Lymphocyte Ratio Related to Patients Outcome in Moderate Head Injury Patients with Intracerebral Hemorrhage

2022

View full text Add to dashboard Cite

Background. Head injury is still a major health problem that is a common cause of disability and death. Moderate head injuries are quite common with outcomes varying patient examination of neutrophils and lymphocytes is quite routinely carried out in health services and the combination of these two values has a stronger predictive value for assessing outcomes in patients because it describes an inflammatory reaction. The GOS is a commonly used scale for classifying patient outcomes. This study aimed to determine the relationship between the ratio of neutrophil-lymphocytes (RNL) to the Glascow outcome scale (GOS) in moderate head injury patients with intracerebral hemorrhage. Methods. This study has a cross-sectional with samples from moderate head injury patients with CT scan images of intracerebral hemorrhage in Dr. M. Djamil Padang in 2021 and 2022. The data comes from medical records and observations of samples that meet the inclusion and exclusion criteria, 36 subjects participated in this study. Results. Most of the subjects (61.1%) were male. A total of 55.6% of subjects had RNL ≥ 7.35 with 44.4% of subjects having poor GOS. In this study, a statistically significant relationship was found between the ratio of neutrophil- lymphocytes in patients with moderate head injury with intracerebral hemorrhage and the Glasgow outcome scale (p-value = 0.005). Conclusion. RNL can predict outcomes in moderate head injury patients with intracerebral hemorrhage.

show abstract

Using the neutrophil-to-lymphocyte ratio to predict outcomes in pediatric patients with traumatic brain injury

Cited by 11 publications

References 32 publications

Comparison of Lymphocyte Neutrophil Ratio in Head Injury Patients with Blood and without Intracranial Bleeding in Dr. M. Djamil Hospital

Comparison of Lymphocyte Neutrophil Ratio in Head Injury Patients with Blood and without Intracranial Bleeding in Dr. M. Djamil Hospital

Comparison of Neutrophil Lymphocyte Ratio in Traumatic Head Injury Patients With and Without Intracranial Hemorrhage at Dr. M. Djamil Hospital

Neutrophil-Lymphocyte Ratio Related to Patients Outcome in Moderate Head Injury Patients with Intracerebral Hemorrhage

Contact Info

Product

Resources

About