Using stated preference discrete choice modelling to evaluate the introduction of varicella vaccination

Hall, Jane; Kenny, Patricia; King, Madeleine; Louviere, Jordan J.; Viney, Rosalie; Yeoh, Angela

doi:10.1002/hec.694

Cited by 139 publications

(134 citation statements)

References 17 publications

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“…To examine the predicted uptake of CRC screening based on our results, we applied previously proposed models to our data (Hall et al, 2002;Gerard et al, 2008). We also investigated the effect of changing the characteristics, as identified by the results of our multinomial logit model, on the expected uptake of CRC screening.…”

Section: Discussionmentioning

confidence: 99%

Preferences for colorectal cancer screening strategies: a discrete choice experiment

et al. 2010

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BACKGROUND: Guidelines underline the role of individual preferences in the selection of a screening test, as insufficient evidence is available to recommend one screening test over another. We conducted a study to determine the preferences of individuals and to predict uptake for colorectal cancer (CRC) screening programmes using various screening tests. METHODS: A discrete choice experiment (DCE) questionnaire was distributed among naive subjects, yet to be screened, and previously screened subjects, aged 50 -75 years. Subjects were asked to choose between scenarios on the basis of faecal occult blood test (FOBT), flexible sigmoidoscopy (FS), total colonoscopy (TC) with various test-specific screening intervals and mortality reductions, and no screening (opt-out). RESULTS: In total, 489 out of 1498 (33%) screening-naïve subjects (52% male; mean age±s.d. 61±7 years) and 545 out of 769 (71%) previously screened subjects (52% male; mean age±s.d. 61±6 years) returned the questionnaire. The type of screening test, screening interval, and risk reduction of CRC-related mortality influenced subjects' preferences (all Po0.05). Screening-naive and previously screened subjects equally preferred 5-yearly FS and 10-yearly TC (P ¼ 0.24; P ¼ 0.11), but favoured both strategies to annual FOBT screening (all P-values o0.001) if, based on the literature, realistic risk reduction of CRC-related mortality was applied. Screening-naive and previously screened subjects were willing to undergo a 10-yearly TC instead of a 5-yearly FS to obtain an additional risk reduction of CRC-related mortality of 45% (Po0.001). CONCLUSION: These data provide insight into the extent by which interval and risk reduction of CRC-related mortality affect preferences for CRC screening tests. Assuming realistic test characteristics, subjects in the target population preferred endoscopic screening over FOBT screening, partly, due to the more favourable risk reduction of CRC-related mortality by endoscopy screening. Increasing the knowledge of potential screenees regarding risk reduction by different screening strategies is, therefore, warranted to prevent unrealistic expectations and to optimise informed choice.

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Section: Discussionmentioning

confidence: 99%

Preferences for colorectal cancer screening strategies: a discrete choice experiment

et al. 2010

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“…On the other hand, at least two qualifications are in order. First, it was not possible to use stated WTP values as predictors of individual choices, which often constitutes the ultimate objective of such an exercise (Hall et al, 2002). Second, in Swiss health care insureds are still used to a degree of cost sharing, which serves to make a decision situation involving out-of-pocket cost less hypothetical than in countries with comprehensive coverage or a national health service.…”

Section: Discussionmentioning

confidence: 99%

Validity of discrete-choice experiments evidence for health risk reduction

Telser

Zweifel

2007

Applied Economics

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Standard-Nutzungsbedingungen:Die Dokumente auf EconStor dürfen zu eigenen wissenschaftlichen Zwecken und zum Privatgebrauch gespeichert und kopiert werden.Sie dürfen die Dokumente nicht für öffentliche oder kommerzielle Zwecke vervielfältigen, öffentlich ausstellen, öffentlich zugänglich machen, vertreiben oder anderweitig nutzen.Sofern die Verfasser die Dokumente unter Open-Content-Lizenzen (insbesondere CC-Lizenzen) zur Verfügung gestellt haben sollten, gelten abweichend von diesen Nutzungsbedingungen die in der dort genannten Lizenz gewährten Nutzungsrechte. Terms of use: Documents in

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“…A number of different methods can be used to obtain and develop attributes for DCEs including literature reviews, 48 expert reviews 49 and focus groups or interviews. 50 Experts in the field do, however, recommend that qualitative work is conducted in order to develop such attributes 47 and interviews are considered by Coast et al 51 as providing the greatest 'richness' of attributes.…”

Section: Development Of Discrete Choice Experiments Attributesmentioning

confidence: 99%

A cluster randomised trial of strategies to increase cervical screening uptake at first invitation (STRATEGIC)

Kitchener

Gittins

Rivero‐Arias

et al. 2016

Health Technol Assess

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BackgroundFalling participation by young women in cervical screening has been observed at a time that has seen an increase in the incidence of cervical cancer in the UK in women aged < 35 years. Various barriers to screening have been documented, including fear, embarrassment and inconvenience.ObjectivesTo measure the feasibility, clinical effectiveness and cost-effectiveness of a range of interventions to increase the uptake of cervical screening among young women.DesignA cluster randomised trial based on general practices performed in two phases.SettingPrimary care in Greater Manchester and the Grampian region in Scotland.ParticipantsPhase 1: 20,879 women receiving their first invitation for cervical screening. Phase 2: 10,126 women who had not attended by 6 months.InterventionsPhase 1: pre-invitation leaflet or not, and access to online booking (Manchester only). Phase 2: (1) vaginal self-sampling kits (SSKs) sent unrequested (n = 1141); or (2) offered on request (n = 1290); (3) provided with a timed appointment (n = 1629); (4) offered access to a nurse navigator (NN) (n = 1007); or (5) offered a choice between a NN or a SSK (n = 1277); and 3782 women in control practices.Main outcome measuresUplift in screening compared with control practices, cost-effectiveness of interventions, and the women’s preferences explored in a discrete choice experiment.ResultsThe pre-invitation leaflet and offer of online booking were ineffective when compared with control practices at 3 months, 18.8% versus 19.2% [odds ratio (OR) 0.96, 95% confidence interval (CI) 0.88 to 1.06;p = 0.485] and 17.8% versus 17.2% (OR 1.02, 95% CI 0.87 to 1.20;p = 0.802), respectively. The uptake of screening at 3 months was higher among previously human papillomavirus (HPV)-vaccinated women than unvaccinated women, 23.7% versus 11% (OR 2.07, 95% CI 1.69 to 2.53;p < 0.001). Among non-attenders, the SSK sent intervention showed a statistically significant increase in uptake at 12 months post invitation, 21.3% versus 16.2% (OR 1.51, 95% CI 1.20 to 1.91;p = 0.001), as did timed appointments, 19.8% versus 16.2% (OR 1.41, 95% CI 1.14 to 1.74;p = 0.001). The offer of a NN, a SSK on request, and a choice between timed appointments and NN were ineffective. Overall, there was a gradual rather than prompt response, as demonstrated by uptake among control practices. A discrete choice experiment indicated that women invited who had not yet attended valued the attributes inherent in self-sampling. The health economic analysis showed that both timed appointments and unsolicited SSK sent were likely to be cost-effective at a cost per quality-adjusted life-year (QALY) gained of £7593 and £8434, respectively, if extended across the national 25-year-old cohort throughout the duration of screening. The certainty of these being cost-effective at a ceiling ratio of £20,000 per QALY gained was > 90%.ConclusionWomen receiving their initial screening invitation frequently delay taking up the offer and the net impact of interventions was small. Timed appointments and SSKs sent to non-attenders at 6 months are likely to be a cost-effective means of increasing uptake and should be considered further. HPV vaccination in the catch-up programme was associated with an increased uptake of cervical screening. Future work should focus on optimising self-sampling in terms of age range, timing of offer for non-attenders and use of urine testing instead of vaginal samples.Trial registrationCurrent Controlled Trials ISRCTN52303479.FundingThis project was funded by the NIHR Health Technology Assessment programme and will be published in full inHealth Technology Assessment; Vol. 20, No. 68. See the NIHR Journals Library website for further project information.

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Using stated preference discrete choice modelling to evaluate the introduction of varicella vaccination

Cited by 139 publications

References 17 publications

Preferences for colorectal cancer screening strategies: a discrete choice experiment

Preferences for colorectal cancer screening strategies: a discrete choice experiment

Validity of discrete-choice experiments evidence for health risk reduction

A cluster randomised trial of strategies to increase cervical screening uptake at first invitation (STRATEGIC)

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