The efficient implementation of many-body interactions in superconducting circuits allows for the realization of multipartite entanglement and topological codes, as well as the efficient simulation of highly correlated fermionic systems. We propose the engineering of fast multiqubit interactions with tunable transmon-resonator couplings. This dynamics is obtained by the modulation of magnetic fluxes threading superconducting quantum interference device loops embedded in the transmon devices. We consider the feasibility of the proposed implementation in a realistic scenario and discuss potential applications.PACS numbers: 03.67. Lx, 42.50.Pq, 85.25.Cp Superconducting qubits coupled to transmission line resonators have proved to be physical systems well suited for quantum information processing [1, 2]. The coherent control performed on this kind of device at the quantum level has produced a series of remarkable results [3][4][5]. It has been proven that this quantum platform can reach ultrastrong-coupling regimes [6,7]. Among superconducting qubits, transmon qubits are currently the most robust and reliable. They are designed in order to suppress offset charge noise to negligible values [8]. Protocols of quantum information have been implemented, such as error correction up to three qubits [9] and experimental tests of fundamental quantum mechanics [10]. Implementations of quantum simulators of spin and coupled spin-boson systems have been recently proposed [11,12]. Complex entangled states encoded in superconducting transmon qubits have already been proposed and realized experimentally [13][14][15]. However, state-of-the-art realizations of many-qubit entangled states still rely on complex sequences of gates, and implementations of effective many-body interactions represent a tough challenge.The introduction of collective entangling operations in superconducting devices can ease several tasks of quantum information processing. They have been proposed theoretically [16] and realized experimentally in ion traps up to fourteen qubits [17]. Similarities between iontrap systems and superconducting circuits have been already investigated [18]. By means of collective gates, one can drive the generic many-qubit transition |00 · · · 0 → |11 · · · 1 and prepare multipartite Greenberger-HorneZeilinger states with a single operation. The transition can be obtained with effective simultaneous red and blue sidebands acting upon the ions. The latter have been also demonstrated in a variety of superconducting setups [19][20][21]. Sequences of collective gates, together with local qubit rotations, can i andmplement stabilizer operators [22,23], that can allow for the implementation of topological codes [3]. Recently it has been shown that collective qubit interactions allow for efficient simulation of fermionic dynamics and coupled fermionic-bosonic systems [4, 5].In this Letter, we propose the implementation of effective many-body interactions among several tunablecoupling transmons inside a microwave cavity. We consider thre...