Using respirators and goggles to control exposure to air pollutants in an anatomy laboratory

Akbar-Khanzadeh, Farhang; Pulido, E.

doi:10.1002/ajim.10180

Cited by 15 publications

(8 citation statements)

References 12 publications

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“…Most used a small number of scales (often, a single "comfort" scale). [17][18][19][20][21][22] This study supports the findings of previous analyses that there are several distinct categories of effects. 10 For example, gender differences were observed for the variables reflecting physiologic and facial comfort effects, but gender did not affect the scales more closely related to functional effects (eg, concentration).…”

Section: Discussionsupporting

confidence: 92%

Subjective Response to Respirator Type: Effect of Disease Status and Gender

Harber¹,

Santiago²,

Wu³

et al. 2010

Journal of Occupational &Amp; Environmental Medicine

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Section: Discussionsupporting

confidence: 92%

Subjective Response to Respirator Type: Effect of Disease Status and Gender

Harber¹,

Santiago²,

Wu³

et al. 2010

Journal of Occupational &Amp; Environmental Medicine

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“…In pathology anatomy labs, FA is a wellknown compound traditionally used as a fixative and tissue preservative. Indoor air analyses consistently show that the levels of airborne FA in pathology anatomy labs exceeded recommended exposure criteria (Shaham et al, 2002;Akbar-Khanzadeh and Pulido, 2003). In these settings, absorption of FA occurs mainly through inhalation.…”

Section: Discussionmentioning

confidence: 84%

Cytogenetic and Immunological Effects Associated with Occupational Formaldehyde Exposure

Costa¹,

García-Lestón²,

Coelho³

et al. 2013

Journal of Toxicology and Environmental Health, Part A

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Formaldehyde (FA) is a widely used industrial chemical for which exposure is associated with nasopharyngeal and sinonasal cancer. Based on sufficient evidence of carcinogenicity from human investigations, supporting studies on mechanisms underlying carcinogenesis, and experimental evidence in animals, FA status was recently revised and reclassified as a human carcinogen. The highest level of exposure to FA occurs in occupational settings. Although several studies reported FA ability to induce genotoxic responses in exposed workers, not all findings were conclusive. In addition, published studies on the immunological effects of FA indicate that this compound may be able to modulate immune responses, although data in exposed subjects are still preliminary. In this study a group of pathology anatomy workers exposed to FA was evaluated for cytogenetic and immunological parameters. A control group with similar sociodemographic characteristics and without known occupational exposure to FA was also included. Genotoxicity was evaluated by means of micronucleus (MN) test, sister chromatid exchanges (SCE), and T-cell receptor (TCR) mutation assay. Percentages of different lymphocyte subpopulations were selected as immunotoxic biomarkers. The mean level of FA environmental exposure was 0.36 ± 0.03 ppm. MN and SCE frequencies were significantly increased in the exposed group. A significant decrease of the percentage of B cells in the exposed group was also found. Data obtained in this study indicate that genotoxic and immunotoxic increased risk due to FA occupational exposure cannot be excluded. Implementation of effective control measures along with hazard prevention campaigns may be crucial to decrease the risk.

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“…(7) can be reduced by using a mask and rubber gloves. A local ventilator may be sited at each cadaver table (6), and respirations and goggles can be used to control exposure to FA (12). There are the most conman methods to reduce the FA concentration.…”

Section: Resultsmentioning

confidence: 99%

Subjective Symptoms of Medical Students Exposed to Formaldehyde during a Gross Anatomy Dissection Course

Chen

Harada

Ohmori

et al. 2007

Int J Immunopathol Pharmacol

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The purpose of this study is to investigate the safety of and to try to find the best plan to cope with exposure to FA for students during a gross anatomy dissection course. The FA exposure level and subjective symptoms was estimated. The relationship between exposure to FA and subjective symptoms of irritation were discussed for times; before, in the beginning period, in the middle period, and upon completion of the Anatomy Dissection Course. The geometric means of FA concentration were 32.7 micrograms/m3 (before), 891.3 micrograms/m3 (beginning), 763.3 micrograms/m3 (middle), and 238.9 micrograms/m3 (completion), respectively. Among them, FA-related symptoms were observed in 61.1 percent; 28.0 percent fell strong stress during the course, and 27.4 percent complained that their normal life situation was affected. Our results indicate that such subjective symptoms during the anatomy dissection course were related to the period spent in the anatomy dissection room. Our study suggests that shortening the time of each anatomy dissection practical class and reduction of the number of cadaver tables could help to reduce symptoms.

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Using respirators and goggles to control exposure to air pollutants in an anatomy laboratory

Abstract: The combination of a half-mask respirator and goggles was the most feasible ensemble to control exposure to air pollutants in an anatomy laboratory.

Cited by 15 publications

References 12 publications

Subjective Response to Respirator Type: Effect of Disease Status and Gender

Subjective Response to Respirator Type: Effect of Disease Status and Gender

Cytogenetic and Immunological Effects Associated with Occupational Formaldehyde Exposure

Subjective Symptoms of Medical Students Exposed to Formaldehyde during a Gross Anatomy Dissection Course

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