Using prefrailty to detect early disability

Acosta-Benito, Miguel Ángel; Sevilla-Machuca, Ignacio

doi:10.4103/2230-8229.189106

Cited by 19 publications

(16 citation statements)

References 17 publications

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“…As frailty and pre-frailty syndrome were common in COPD patients, and given that clinical outcomes of patients with frailty could be reversed using multidisciplinary intervention (especially at the pre-frailty stage),27 early recognition of this syndrome among COPD patients is critical. Examining for risk factors, such as comorbid cancer, a history of hospitalization, over-/undernutrition, or sarcopenia (using handgrip strength and gait speed for screening according to the AWGS recommendation), would be beneficial in order for early intervention, such as comprehensive geriatric assessment, physical therapy referral, and nutritional intervention, to take place 2,3,10.…”

Section: Discussionmentioning

confidence: 99%

Frailty syndrome in ambulatory patients with COPD

Limpawattana¹,

Putraveephong²,

Inthasuwan³

et al. 2017

COPD

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Frailty is a state of increased risk of unfavorable outcomes when exposed to stressors, and COPD is one of the several chronic illnesses associated with the condition. However, few studies have been conducted regarding the prevalence of COPD and its related factors in Southeast Asia. The objectives of this study were to determine the prevalence of frailty in COPD patients and to identify the associated factors in these populations. A cross-sectional study of COPD patients who attended a COPD clinic was conducted from May 2015 to December 2016. Baseline characteristics were collected, and the diagnosis of frailty was based on the FRAIL (fatigue, resistance, ambulation, illnesses, and loss of weight) scale. Descriptive statistics were used to analyze baseline data. Factors associated with frailty were analyzed using univariate and multivariate regression analyses. The results showed that the prevalence rates of frailty and pre-frailty were 6.6% (eight out of 121 cases) and 41.3% (50 out of 121 cases), respectively, among COPD patients. Fatigue was the most common component of the FRAIL scale that was found more frequently in frail patients than in non-frail patients (odds ratio [OR] 91.9). Factors associated with frailty according to multivariate analyses were comorbid cancer (adjusted OR [AOR] 45.8), at least two instances of nonelective admission over the past 12 months (AOR 112.5), high waist circumference (WC) (AOR 1.3), and presence of sarcopenia (AOR 29.5). In conclusion, frailty affected 6.6% of stable COPD patients. Cancer, two or more instances of nonelective hospitalization over the past 12 months, high WC, and presence of sarcopenia were associated with frailty. Early identification and intervention in high-risk patients is recommended to prevent or delay the adverse outcomes of frailty.

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Section: Discussionmentioning

confidence: 99%

Frailty syndrome in ambulatory patients with COPD

Limpawattana¹,

Putraveephong²,

Inthasuwan³

et al. 2017

COPD

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“…Frailty and pre-frailty are common in patients with COPD; however, using multidisciplinary intervention, patients with frailty can be reversed, especially at the pre-frailty stage 120. Therefore, it is critical to diagnose frailty at an early stage.…”

Section: Interventionmentioning

confidence: 99%

Frailty assessment in older adults with chronic obstructive respiratory diseases

Guan¹,

Huang²

2018

CIA

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The number of patients with chronic obstructive pulmonary disease (COPD) has been rising with continued exposure to environmental risk factors and aging of populations around the world. Frailty is a geriatric syndrome with a decline in physiological reserve and often coexists with chronic diseases such as COPD. Frailty is an independent risk factor for the development and progression of COPD, and COPD can lead to frailty; treating one might improve the other. Thus, there is an increasing interest in the assessment of frailty in patients with COPD. Furthermore, early identification and assessment of frailty in patients with COPD may affect the choice of intervention and improve its effectiveness. Based on the current literature, the intent of this review was to summarize and discuss frailty assessment tools used for COPD patients and the relevant clinical practices for predicting outcomes. We ascertain that using suitable frailty assessment tools could facilitate physicians to screen and stratify physically frail patients with COPD. Screening appropriately targeted population can achieve better intervention outcomes and pulmonary rehabilitation among frail COPD patients.

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“…Prefrailty is the state between robustness and frailty, in which one or two of the five criteria are met (Blaum, Xue, Michelon, Semba, & Fried, ). As a transitional status between robust and frailty, prefrailty has been reported to be associated with chronic comorbidity (Danon‐Hersch, Rodondi, Spagnoli, & Santos‐Eggimann, ) and functional decline (Acosta‐Benito & Sevilla‐Machuca, ). Frailty has been established to be a risk factor for falls (Kojima, ).…”

Section: Introductionmentioning

confidence: 99%

Falls in community‐dwelling prefrail older adults

Umegaki

Makino

Uemura

et al. 2019

Health Soc Care Community

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Frailty has been established as a risk factor for falls, and prefrailty also seems a risk; however, few studies have focused on the association between falls and each of the five components of frailty proposed by Fried. In the present study, we sought to elucidate the association between prefrailty and falls, and moreover, the association of frailty component with falls. Participants were community‐dwelling older people who had cognitive complaints but not dementia (N = 447, male 54.6%). Prefrailty was defined as exhibiting one or two of the five Fried criteria. Frail individuals were excluded. Background characteristics were compared between the prefrail and robust groups, and multiple regression analysis was performed to investigate the associations between fall history within the past year and factors that were significantly different between the groups. We also performed logistic regression analysis with adjustment for age, education and gender to assess associations with frailty components. We found that prefrailty was associated with fall history. Depressed mood was also significantly associated with fall history. Among the five frailty criteria, exhaustion was significantly associated with falls. Prefrailty, especially the criteria of exhaustion, and depressed mood were associated with fall history.

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Using prefrailty to detect early disability

Cited by 19 publications

References 17 publications

Frailty syndrome in ambulatory patients with COPD

Frailty syndrome in ambulatory patients with COPD

Frailty assessment in older adults with chronic obstructive respiratory diseases

Falls in community‐dwelling prefrail older adults

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